Treatment of Hip Trochanteric Bursitis Using Hyaluronate Injections

Gorelick, Lauren; Rozano-Gorelick, Ayala; Robinson, Dror; Marcus, O D Susannah; Joubran, Samia; Ram, Edward

doi:10.4236/ojra.2013.32019

Cited by 3 publications

(3 citation statements)

References 10 publications

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“…These results are in concordance with those from the only published study performed to date, i.e. using HA injected for treating trochanteric bursitis (although the journal where the manuscript was published is not indexed in JCR) [11]. This retrospec- tive study, that involved the follow-up of at least 12 months of 158 patients with trochanteric bursitis, showed the higher effectiveness of both the single injection of HA and its combination with corticosteroids than the conventional treatment with corticosteroids for treating trochanteric bursitis.…”

Section: Discussionsupporting

confidence: 88%

“…In view of these effects for intra-articular injections, it seems reasonable to extrapolate the same effectiveness to intra-bursal injections for the treatment of GTPS. To date, and with the exception of just one recent study [11], there are no published studies addressing the efficacy of HA injections at the trochanteric bursa in patients with GTPS. Therefore, the objective of the study is to compare the efficacy and safety of HA to corticosteroid injections for the treatment of the GTPS.…”

Section: Introductionmentioning

confidence: 99%

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A Comparative Study between Hyaluronic Acid and Corticosteroids for the Treatment of the Greater Trochanteric Pain Syndrome

Pereira¹,

López²,

Serna

2015

OJRA

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Objective: To date, there are no studies addressing the efficacy of hyaluronic acid (HA) injections at the trochanteric bursa in patients with greater trochanteric pain syndrome (GTPS). The objective of the study was to compare the efficacy and safety of HA to corticosteroid injections for the treatment of the GTPS. Methods: This prospective, randomized, two-arm trial involved 47 patients with unilateral or bilateral GTPS. Patients received an intra-bursal injection of 40 mg triamcinolone acetonide plus 1mL lidocaine, or of 60 mg HA. Patients completed visual analog scales (VAS) and Likert scales to evaluate interference of pain with daily activity, recovery from pain, and treatment satisfaction. A non-inferiority analysis was also performed. Results: Mean VAS score for pain significantly decreased comparing baseline with 1, 3 and 6 months in both treatment groups. VAS score for pain on palpation was also significantly lower than baseline in both arms. No significant differences were found between groups. Analysis of Likert scales at the sixth month didn't detect statistically significant differences between treatment groups. The non-inferiority analysis showed that the treatment with HA was non-inferior to corticosteroids. No secondary adverse effects were found among the patients of both groups during the follow-up. Conclusions: The treatment with HA has demonstrated to be non-inferior to corticosteroids after 6 months of follow-up in patients with GTPS. Therefore, the treatment with HA may be considered an effective alternative therapeutic strategy to reduce pain in patients in whom the treatment with corticosteroids, or other therapies, have been unsuccessful or contraindicated.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

A Comparative Study between Hyaluronic Acid and Corticosteroids for the Treatment of the Greater Trochanteric Pain Syndrome

Pereira¹,

López²,

Serna

2015

OJRA

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“…Injection of corticosteroids is efficacious for short time pain relief but is problematic because of rare severe adverse effects including tendon rupture [1]. There is a growing body of evidence supporting the use of hyaluronate injections in patient with ankle sprain, adhesive capsulitis of the shoulder, patients after flexor tendon injury and hip pathology, although the mechanism of the effect have not yet been clarified [6][7][8][9][10][11]. There is some evidence that hyaluronate significantly increase proliferation of vascular Endothelial Growth Factor (VEGF) and collagen type 4 for up to six weeks after injection.…”

Section: Introductionmentioning

confidence: 99%

Lateral Epicondylitis Injection Therapy: A Safety and Efficacy Analysis of Hyaluronate versus Corticosteroid Injections

Gorelick¹

2015

Adv Tech Biol Med

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Lateral epicondylitis or tennis elbow, is a common elbow malady the extensor carpi radialis brevis origin. It is commonly treated by local injections of steroids are often associated with severe side effects and limited long term efficacy. Recently, hyaluronate is being increasingly used for the treatment of different degenerative processes of joints and soft tissue. Hyaluronate significantly and dose-dependently inhibits cell proliferation and decreased the expression level of mRNA for adhesion-related pro-collagens and cytokines. It is possible that such hyaluronate injections might improve results of injection therapy in tennis elbow syndrome.

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The Greater Trochanteric Pain Syndrome: Clinical Presentation, Diagnosis, and Management

Guemara

Nissén

2023

Curr Treat Options in Rheum

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Purpose of Review This review describes the greater trochanteric pain syndrome in terms of its clinical presentation, diagnosis, and management. Recent Findings We emphasized recent studies including emerging therapies such as radiofrequency ablation of the trochanteric branches of the femoral nerve and new surgical therapies such as minimal invasive surgery and gluteal reconstruction. Summary We describe conservative therapies, such as lifestyle modifications and physical therapy and pharmacological approaches including local injections, as well as surgical procedures. Until recently, local injections involved the use of only local anesthetic and/or corticosteroid; however, recent studies have suggested a potential role for platelet-rich plasma or hyaluronic acid. In the absence of a gluteal tear or rupture, management is initially focused on the use of analgesics to control pain, lifestyle measures, and prolonged physical therapy to improve local muscle strength, followed by the addition of local extracorporeal shock wave therapy. If symptoms persist, a new approach involves an injection of local anesthetic, potentially followed by a corticosteroid or platelet-rich plasma injection, based on the response to the initial anesthetic injection. In the case of refractory pain or tendon rupture, surgical treatment may be indicated, depending on the age of the patient and the degree of local muscle atrophy and fatty infiltration.

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Treatment of Hip Trochanteric Bursitis Using Hyaluronate Injections

Cited by 3 publications

References 10 publications

A Comparative Study between Hyaluronic Acid and Corticosteroids for the Treatment of the Greater Trochanteric Pain Syndrome

A Comparative Study between Hyaluronic Acid and Corticosteroids for the Treatment of the Greater Trochanteric Pain Syndrome

Lateral Epicondylitis Injection Therapy: A Safety and Efficacy Analysis of Hyaluronate versus Corticosteroid Injections

The Greater Trochanteric Pain Syndrome: Clinical Presentation, Diagnosis, and Management

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