Treatment of Hidradenitis Suppurativa

Newell, Gordon B.; Voelter, William W.; Mullins, J. Fred

doi:10.1001/jama.1973.03220050056019

Cited by 13 publications

(3 citation statements)

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“…Intralesional corticosteriods are of benefit for patients with an isolated number of tender lesions (54). Practically, such treatment may not be appropriate for individuals with extensive disease.…”

Section: Managementmentioning

confidence: 99%

Hidradenitis suppurativa: a review

2004

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Hidradenitis suppurativa is a recurrent disease involving apocrine-bearing skin with a predilection for intertriginous areas, including genital skin. It has a highly variable clinical course. Mild cases may present as recurrent isolated nodules, while severe instances of the disease with chronic inflammation may lead to scarring, functional impairment, and rarely, squamous cell carcinoma. While genetic factors, patient characteristics, hormones and infection play a role in disease expression, a comprehensive understanding of the pathogenesis remains to be elicited. Additionally, effective treatment is largely unknown. While the mainstay of therapy had been surgery, and topical or systemic antimicrobial agents, other therapeutic modalities such as retinoids, hormonal therapy and immunosuppresive medications may also hold some promise.

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Section: Managementmentioning

confidence: 99%

Hidradenitis suppurativa: a review

2004

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“…13 Isolated lesions can respond to intralesional corticosteroid injection. 14 Some case reports exist for the use of systemic corticosteroids, cyclosporine, and azathioprine. 15 Methotrexate is reported to have minimal benefit in treating HS.…”

mentioning

confidence: 99%

Hidradenitis Suppurativa in 64 Female Patients: Retrospective Study Comparing Oral Antibiotics and Antiandrogen Therapy

2007

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“…Although antibiotics are not curative, they may diminish odour and discharge, and reduce pain. Systemic 86 or intralesional 87 corticosteroids have been used with variable results, but may be of transient benefit in some patients.…”

Section: Treatmentmentioning

confidence: 99%

Acne inversa (alias hidradenitis suppurativa)

Jansen

Altmeyer

Plewig

2001

Acad Dermatol Venereol

112

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Acne inversa is a recurrent, suppurative disease manifested by abscesses, fistulas, and scarring. Once considered to be a disease of the apocrine glands, it is actually a defect of follicular epithelium. Thus, the term hidradenitis suppurativa is a misnomer and should be abandoned. In cases of familial acne inversa, the pattern of transmission and number of affected individuals are consistent with autosomal dominant inheritance. Aetiological factors such as hyperandrogenism, obesity, smoking and chemical irritants are not consistently associated with the affection. Bacterial involvement is not a primary event in acne inversa, but is secondary to the disease process. Potential complications include dermal contraction, local or systemic infection due to the spread of microorganisms, systemic amyloidosis, arthropathy, and squamous cell carcinoma. As spontaneous resolution is rare and progressive disability is the rule, early definitive surgical intervention is advisable. The surgical procedure of choice in most cases is wide local excision and healing by secondary intention. Pharmacotherapeutic drugs, including synthetic retinoids and antiandrogens, do not prevent progression of the disease.

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Treatment of Hidradenitis Suppurativa

Cited by 13 publications

References 1 publication

Hidradenitis suppurativa: a review

Hidradenitis suppurativa: a review

Hidradenitis Suppurativa in 64 Female Patients: Retrospective Study Comparing Oral Antibiotics and Antiandrogen Therapy

Acne inversa (alias hidradenitis suppurativa)

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