Treatment of Herpes Simplex with 5-Iodo-2'-deoxyuridine

Treatment of Herpes Simplex Lessions of the Face with Idoxuridine: Results of a Double-blind Controlled Trial

“…when it was compared with neomycin ointment in the treatment of keratitis in man it seemed imperative to examine its effect on skin lesions in a double-blind controlled trial. The type of ointment and its source was the same' as that used by Hall-Smith et al (1962).…”

The Riddle of Uveitis

“…This pathway in viral synthesis may ,be interrupted by the halogenated pyrimidines, that most frequently used in clinical practice being 5-iodo-2' deoxyuridine (IDU) (Kaufman, Nesburn and Maloney 1962;Hall-Smith, Corrigan and Gilkes 1962). Inhibitory effects have been noted against herpes simplex, vaccinia and adenovirus, but viruses whose genetic information is in the form of RNA are unaffected by this group of compounds.…”

Herpesvirus Hominis (Virus of Herpes Simplex)1

“…The use of the word Herpes, as applied to certain manifestations of skin disease, has a long tradition, starting with Hippocrates. The many interpretations of its meaning through 25 centuries were discussed in a scholarly review by Beswick (9), who pointed out that the first author to give a clear account of the disease Herpes Febrilis was Richard Morton in 1694, but that it was not until the end of the 19th century 1 A contribution to the Symposium on "Current Progress in Virus Diseases" presented as part of the program for the Centennial of the Boston City Hospital, 1 June 1964, with Maxwell Finland serving as Consultant Editor, and John H. Dingle and Herbert R. Morgan as moderators.…”