Treatment of esthesioneuroblastoma: A 16‐year meta‐analysis of 361 patients

Abstract

These results suggest that endoscopic surgery is a valid treatment method with comparable survival to open surgery. Further prospective analysis will be beneficial.

Esthesioneuroblastoma: A case with prolonged disease control

“…This is supported by several studies that demonstrated superior outcomes for this combined approach when compared to just undergoing surgery or radiotherapy alone [9,[21][22][23][24][25][26][27][28][29][30] . In the meta-analysis by Dulguerov et al [3] , patients treated by surgery and radiotherapy had a 5y-OS of 65%.…”

Olfactory Neuroblastoma Treated by Minimally Invasive Endoscopic Resection and Postoperative Adjuvant Radiotherapy: A Representative Case and an Updated Review of the Literature

“…Combined transfacial and neurosurgical conventional approaches are adopted in several cases, mainly due to the endocranial extension and the close anatomic relationship of esthesioneuroblastomas with the ethmoid roof and cribriform plate [20][21][22]. The role of open surgery is quite well established through the years and is supported by extended literature.…”

“…The role of open surgery is quite well established through the years and is supported by extended literature. Such approaches usually allow en bloc resection of the tumor, ensuring protection of both brain and optic nerve [5,17,22].…”

“…Although there are more cases of long term follow-up in the open surgery group, it is quite interesting that endoscopic approaches are usually reported to produce equal or better survival rates than open surgery [5,[6][7][8], even when data is stratified for publication year. However, it should be taken into account that tumors treated with open surgery techniques are usually staged as Kadish C and D, whereas endoscopic surgery is more commonly restricted to Kadish A and B lesions [5,22]. Despite of this fact, most studies support that endoscopic resection correlates with similar oncologic control rates, compared with conventional open surgery, provided that basic surgical principles, with clearance of margins and intradural dissection (when required), are completely maintained [5-7, 22,23].…”

Endonasal Endoscopic Anterior Skull Base Surgery for Sinonasal Malignancies: Juntendo’s Experience

“…Prior works showed that the results with an endoscopic approach appeared equivalent to those for cranioendoscopic approaches in adenocarcinoma and squamous cell carcinomas 22) . In a meta-analysis of 23 articles on esthesioneuroblastoma in 361 patients that compared endoscopic with open surgery 15) , endoscopic surgery was associated with better survival (10-year overall survival rate of 90% versus 65% for open surgery). Since most of the open surgery patients were advanced cases, the use of endoscopic surgery is recommended for earlystage esthesioneuroblastoma 22) , adenocarcinoma 23) , chondrosarcoma 24) , and malignant melanoma 25) .…”