Treatment of emphysema using bronchoscopic lung volume reduction coil technology: an update on efficacy and safety

Hartman, Jorine E.; Klooster, Karin; Hacken, Nick H. T. ten; Slebos, Dirk‐Jan

doi:10.1177/1753465815589904

Cited by 15 publications

(9 citation statements)

References 18 publications

(71 reference statements)

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“…The SGQR response at 90 days after final treatment was greater than in the usual care group and > 60% of the patients in BVR group experienced improvement in FEV 1 and no significant adverse event was reported. It is also confirmed that BVR using coils are safe and with no late pneumothoraces, coil migration or unexpected adverse events by Hartman et al [19]. According to this study, 3 [16][17][18][19][20] years after treatment 50% of the patients maintained an improvement 6MWT, SGRQ and dyspnea scores.…”

Section: Coilssupporting

confidence: 86%

Bronchoscopic treatment options for chronic obstructive pulmonary disease

Yıldızeli¹

2016

MMJ

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Chronic obstructive pulmonary disease (COPD) is a major cause of high mortality and morbidity worldwide. Symptoms of the disease are usually related with the results of pulmonary dynamic hyperinflation. Treatment options are classified as invasivenoninvasive and mostly tend to be palliative. Lung volume reduction techniques are invasive part of the treatment and can be performed by surgical or bronchoscophic methods. Because of the low complication rates bronchoscophic methods became more popular in recent years. Patients presenting with severe air trapping and thoracic hyperinflation have the greatest potential to derive benefit from volume reduction procedures. Assessment of patients should ideally include cardiological evaluation, high resolution CT scan, ventilation and perfusion scintigraphy, full pulmonary function tests, and cardiopulmonary exercise testing.There are three main groups of bronchoscophic volume reduction, direct effect on lung parenchyma, airway bypass and blocking the airways. Indications and contraindications are different for each modality and device. Patients who have deterioration despite habitual changes and medical therapies should be evaluated for volume reduction procedures.

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Section: Coilssupporting

confidence: 86%

Bronchoscopic treatment options for chronic obstructive pulmonary disease

Yıldızeli¹

2016

MMJ

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“…To put the cost of the EBV treatment in perspective, we compared the costs‐effectiveness analyses of other treatments for advanced emphysema patients such as lung volume reduction coil treatment, LVRS and lung transplantation. Another bronchoscopic lung volume reduction treatment option is the treatment with coils . The REVOLENS trial investigated the lung volume reduction coil treatment and reported an ICER of $782 598 (approximately €738 400) per additional QALY, calculated over a 1‐year period .…”

Section: Discussionmentioning

confidence: 99%

Cost‐effectiveness of endobronchial valve treatment in patients with severe emphysema compared to standard medical care

et al. 2018

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“…Coils are a potential treatment option for patients who do not qualify for endobronchial valve treatment [due to for example positive interlobar collateral ventilation status (16)] or lung volume reduction surgery, and can also be offered as a bridge to lung transplantation. Selecting optimally treated, symptomatic COPD patients with emphysema and severe hyperinflation (absolute minimal criteria for hyperinflation: RV >200% predicted and RV/TLC ratio >58%, measured using body plethysmography), while avoiding significant airway disease such as asthma, chronic bronchitis and bronchiectasis, is key to achieve treatment success (12,28,29). Additional patient inclusion and exclusion criteria specific for the coil treatment from our center are summarized in Table 3.…”

Section: Patient Selection Criteriamentioning

confidence: 99%

Lung volume reduction with endobronchial coils for patients with emphysema

Welling

Slebos

2018

J. Thorac. Dis.

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The lung volume reduction coil treatment is a minimally invasive bronchoscopic treatment option for emphysema patients who suffer from severe hyperinflation. The treatment is aimed at a large group of patients where lung volume reduction surgery and bronchoscopic lung volume reduction using endobronchial valves are no option, or alternatively, can be offered as a bridge to lung transplantation. The nitinol coil exhibits a shape memory effect and is biologically inert. The lung volume reduction coil procedure is performed in two separate treatment sessions, targeting one lobe per session, with the contralateral lobe being treated 4 to 8 weeks after the first session. In one treatment session, around 10 to 14 coils, thereby treating an entire lobe, are being placed. Selecting optimally treated, symptomatic chronic obstructive pulmonary disease (COPD) patients with emphysema and severe hyperinflation, while avoiding significant airway disease such as asthma, chronic bronchitis and bronchiectasis, is key to achieve treatment success. Three randomized clinical trials investigating lung volume reduction coil treatment have been published until now, reporting the results of 452 treated patients up to 12 months after coil treatment. Lung volume reduction coil treatment results in significant improvement of pulmonary function outcomes and quality of life in patients with severe hyperinflation. The most common complications of lung volume reduction coil treatment are: COPD exacerbations, pneumonia, Coil Associated Opacity and an increased risk of pneumothorax. The purpose of this article is to describe the coil technique and review the available literature regarding effect, safety and future perspectives of lung volume reduction with coils for emphysema patients.

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Treatment of emphysema using bronchoscopic lung volume reduction coil technology: an update on efficacy and safety

Cited by 15 publications

References 18 publications

Bronchoscopic treatment options for chronic obstructive pulmonary disease

Bronchoscopic treatment options for chronic obstructive pulmonary disease

Cost‐effectiveness of endobronchial valve treatment in patients with severe emphysema compared to standard medical care

Lung volume reduction with endobronchial coils for patients with emphysema

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