Treatment of depression during pregnancy: a protocol for systematic review and meta-analysis
Larissa Junkes,
Bruno Rabinovici Gherman,
Jose Carlos Appolinario
et al.
Abstract:IntroductionMajor Depressive Disorder (MDD) is a chronic, recurrent, and highly prevalent disease that is associated with significant functional disability. During pregnancy, the prevalence of the disease is approximately 20%, with 12% of these, requiring treatment to avoid important negative consequences for the mother-baby binomial. Risk-benefit assessment of the use of antidepressants during pregnancy is mandatory, in addition to knowledge of the long-term effects of prenatal exposure to these drugs in the … Show more
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