Treatment of Cutaneous Melanoma of the Face by Mohs Micrographic Surgery

Abstract

Mohs micrographic surgery appears to be an effective treatment for facial melanomas. Our study showed complete correlation between frozen section tissue margins and permanent section controls.

Mohs micrographic surgery in the treatment of lentigo maligna and melanoma

“…We previously reported a 6 years experience of 97 patients with melanoma of the face, successfully treated with MMS [22]. Herein, we expand upon this early experience to include 202 cases performed over a decade, including all anatomic sites.…”

Presentation, Histopathologic Findings, and Clinical Outcomes in 7 Cases of Melanoma In Situ of the Nail Unit

“…Studies of long-term survival in patients with melanoma support the conclusion that physicians trained in examining frozen sections can accurately identify subclinical extension of melanoma. 16,17 However, other paired comparisons of frozen sections vs paraffin embedding have demonstrated increased diagnostic accuracy with permanent techniques. [18][19][20] Currently, our dermatologic surgery division uses frozen sections, occasionally with immunohistochemi- …”

Management of lentigo maligna and lentigo maligna melanoma: Seminars in surgical oncology

“…The most frequent site of LMM is on the cheek. Males and females have the same distribution of lesions on the cheeks and nose while women have a 2.5 times greater chance of having a lesion on the forehead and men a 3.1 times greater incidence on the ears [11]. Extra facial LMMs have been reported on the trunk and limbs [16].…”

“…MMS used to treat 97 patients with facial melanoma revealed no cases of local recurrence over 48 month [11]. This initial series has been expanded to 202 cases treated over a 10-year period [61].…”

“…LM occurs at an average age of 63 [11] and LMM at 73 years of age [12,13]. The average age for other histogenetic forms of CMM is 47-53 years of age [12,14].…”