Treatment of cosmetic tattoos with nonablative fractional laser in an animal model: A novel method with histopathologic evidence

Wang, Chia Chen; Huang, Chuen Lin; Lee, Shao Chen; Sue, Yuh Mou; Leu, Fur-Jiang

doi:10.1002/lsm.22086

Cited by 17 publications

(10 citation statements)

References 27 publications

(32 reference statements)

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“…Laser-induced transepidermal elimination has been reported in previous studies after CO2 resurfacing or nonablative 1,550-nm erbium:glass fractional laser treatment. 9,10 Because only a limited portion of the XP lesions was treated with the CO2 laser in our patient, marked clinical improvement could have resulted from transepidermal elimination of the target tissues by the pinhole method.…”

Section: Discussionmentioning

confidence: 98%

Treatment of Xanthelasma Palpebrarum by the Pinhole Method Using a 10,600-nm Carbon Dioxide Laser

Ahn

Kang²,

Cho³

2013

Medical Lasers

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Xanthelasma palpebrarum (XP) presents clinically as yellowish plaques on the upper and/or lower eyelids. To date, several studies have reported on the therapeutic efficacies of ablative and non-ablative lasers for treatment of XP, including 10,600-nm carbon dioxide (CO2) lasers, erbium-doped yttrium aluminum garnet (YAG) lasers, 1,550-nm erbiumdoped fractional lasers, pulsed dye lasers, Q-switched neodymium: YAG lasers, and 1,450-nm diode lasers. Here, we report on a case of XP effectively treated using the pinhole method. The pinhole method utilized a CO2 laser in order to make multiple small holes, which mimicked sweat pores on skin lesions. CO2 lasers are among the most widely available laser devices; therefore, implementation of their use in performance of the pinhole procedure for treatment of XP in Asian patients would be relatively easy and inexpensive.

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Section: Discussionmentioning

confidence: 98%

Treatment of Xanthelasma Palpebrarum by the Pinhole Method Using a 10,600-nm Carbon Dioxide Laser

Ahn

Kang²,

Cho³

2013

Medical Lasers

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“…Cosmetic tattoos are traditionally treated by Q-switched lasers without satisfactory results. Since the introduction of fractional laser, Wang et al [10] studied the effect of a 1,550 nm, erbium-glass fractional laser system to remove cosmetic non-black colored tattoos. They used the energy settings of 17 mJ and 169 MTZ/cm 2 , 2 passes (total density of 338 MTZ/cm 2 ) for five sessions at 1 month intervals on rats.…”

Section: Cosmetic Tattoosmentioning

confidence: 99%

The Treatment of Pigmented Lesions in Taiwan

Chen¹

2017

Pigmentary Disorders

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Combined dyspigmentation such as lentigines intermingled with freckles, or melasma with acquired bilateral nevus of Ota-like macules, are common among women in Taiwan. There are various lasers available, including Qswitched Nd-YAG laser, Q-switched alexandrite laser, Q-switched ruby laser, and pico laser. We conducted a literature review to understand the current practice of treatment for pigmented lesions in Taiwan.

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“…conventional q-switched lasers and are indications of allergic reactions. 11,27 So far, the removal of ink particles has been demonstrated for both AFXL 28 and NAFXL 29 procedures. It would be more than interesting if this concept could be extended to other granuloma, fungi, or parasites.…”

Section: Removal Of Foreign Bodies Such As Tattoo Ink and Fillermentioning

confidence: 99%

The Future of Fractional Lasers

Paasch

2016

Facial plast Surg

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The human skin is one of the biggest organs in terms of surface. As humans grow older, more and more people are affected by skin diseases. Although a skin disease may be addressed easily due to its accessibility, the complex structure and function of it often prevent side effect-free interventions.The observation that a fractionated treatment of the skin leads to improved results as compared with that which can be achieved by treating the whole affected area is not new. In vessels, it has been discovered that there is no need to address the structure in total along its way under the skin. In addition, there were superior cosmetic results when only parts of the vasculature were coagulated whereas intact structures did not diminish the results.Fractional lasers are named after their characteristic to deliver a laser light onto fractions or parts of the skin surface. 1By doing so, it came to our attention that the biggest human organ in size is able to replace itself up to 50% within only 4 to 6 weeks if the individual piece of skin taken out is less than 0.3 mm in diameter. These columns of treated skin can go as deep as the entire integument and are called microscopic treatment zones (MTZ). As fractional lasers enable us to trigger a skin remodeling in both the epidermal and the dermal compartment, they have found a wide acceptance in a rather short time. On a cellular level, the post-fractional wound healing is defined by a stereotypical sequence of processes, mainly triggered by the activation of heat shock proteins (HSPs) within the remaining keratinocytes, culminating in an active expulsion of pigmented irreparable tissue parts (microscopic epidermal necrotic debris [MEND]) 3 days later. 2Despite a wide use of fractional lasers to treat several skin conditions associated with aging and trauma, the door has just been opened in terms of using this extremely high capacity of self-renewal in the context of treating skin cancers, fibrosing skin diseases, inflammatory and granulomatous skin conditions, as well as infectious diseases. This review aims at summarizing the current status of fractional lasers in daily clinical routine as well as the underlying technology, and it provides an outlook for ways in which the as yet unused potential can be transferred to clinics. Basic Concepts and MechanismsIn the past it has been shown that wounding in particular results in a typical sequence of healing, which is most often accompanied by inflammation. To specifically address skin remodeling in sun-damaged or aged skin for a long time, socalled skin resurfacing has been used. Lasers that have been AbstractRecent insights to the potential of fractional skin treatments have established standard laser procedures to treat aged, sun-damaged skin and scars. On top of this, the concept has been extended to fibrosing conditions, to remove foreign bodies and to treat inflammatory skin diseases. The biggest potential, however, is foreseen with the option of a contact-free temporary opening of the epidermal barrier (TOR, German: gate)...

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Treatment of cosmetic tattoos with nonablative fractional laser in an animal model: A novel method with histopathologic evidence

Abstract: Nonablative fractional lasers (NAFLs) successfully remove cosmetic tattoos by transepidermal elimination of tattoo pigments through the disrupted dermal-epidermal junction. This action is facilitated by the wound healing process.

Cited by 17 publications

References 27 publications

Treatment of Xanthelasma Palpebrarum by the Pinhole Method Using a 10,600-nm Carbon Dioxide Laser

Treatment of Xanthelasma Palpebrarum by the Pinhole Method Using a 10,600-nm Carbon Dioxide Laser

The Treatment of Pigmented Lesions in Taiwan

The Future of Fractional Lasers

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