Treatment of Congenital Melanocytic Naevi With CO2 Laser

Horner, Ben; El-Muttardi, Naguib; Mayou, B.J.

doi:10.1097/01.sap.0000174365.31469.45

Cited by 33 publications

(31 citation statements)

References 21 publications

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“…Lasers used for the treatment of CMN include pigment‐specific lasers, 1–3 resurfacing lasers, 4,5 and more recently, a combination of the two 2,6 , 7 . The pigment‐specific group include the Q‐switched ruby laser, 1 the Q‐switched alexandrite laser 2 and the Q‐switched Nd:YAG laser 3 .…”

Section: Reportmentioning

confidence: 99%

Er:YAG laser resurfacing for inoperable medium-sized facial congenital melanocytic naevi in children

2007

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Congenital melanocytic naevi (CMN) can cause significant psychosocial morbidity, especially if they are in visually exposed areas. The preferred treatment is surgical excision, though not all lesions are amenable to this because anatomical location may preclude aesthetic and functional reconstruction. Three children with inoperable facial CMN were treated with Er:YAG resurfacing under general anaesthetic. Two children were Fitzpatrick skin type II, and one child was skin type VI. Treatment was performed at 4-9-monthly intervals. The procedure achieved significant lightening and thinning in all three cases, without scarring or dyspigmentation. One child developed herpes simplex infection in the treated area on one occasion, which was managed with oral aciclovir, and did not lead to scarring or preclude further treatment. We conclude that Er:YAG laser resurfacing is effective for CMN, even in darker skin types. The incidence of side-effects is low, although repeated treatment is necessary.

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Section: Reportmentioning

confidence: 99%

Er:YAG laser resurfacing for inoperable medium-sized facial congenital melanocytic naevi in children

2007

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“…62 Authors advocating the use of the carbon dioxide laser offer the rationale that the risk of melanoma in giant congenital melanocytic nevi is small and that when melanoma develops, it often does so in sites distant from the giant nevus. 50 Horner et al 63 used the carbon dioxide laser in 12 patients in childhood and achieved considerable aesthetic improvement, but 50 percent of their patients developed hypertrophic scarring. Reynolds et al 50 primarily used the carbon dioxide laser in children in the first year of life and achieved acceptable aesthetic results.…”

Section: Lasersmentioning

confidence: 98%

Giant Congenital Melanocytic Nevi

Arneja

Gosain

2007

Plastic and Reconstructive Surgery

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“…Although normal-mode ruby, QS, and normal-mode 755-nm alexandrite; QS 532-nm, and 1,064-nm Nd:YAG; 585nm pulsed dye laser (PDL); and the ablative laser systems may improve the clinical appearance of acquired, blue, or congenital melanocytic nevi, dermal melanocytic nevoid cells often remain after treatment and pose a risk for malignant transformation. [32][33][34][35][36][37][38][39][40][41][42][43][44] In general, the longer wavelength lasers are better adapted to reach deeply situated melanocytes to treat blue, congenital, compound, or dermal nevi. The risk of malignant transformation, in addition to the side effects of each type of laser, should be discussed with the patient prior to treatment.…”

Section: Melanocytic Nevimentioning

confidence: 99%

18 The Use of Lasers for Skin Pathology

Truswell¹

2016

Lasers and Light, Peels and Abrasions

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The use of lasers for skin pathology has grown dramatically since their initial introduction several decades ago. The quantum theory of radiation, described nearly a century ago, served as the theoretical foundation for the development of lasers. Yet it was not until 1959 that Maiman developed the first laser 1 and later, in 1963, when Dr. Leon Goldman pioneered laser therapy for the field of dermatology by treating various cutaneous conditions with his ruby laser. Laser therapy was further revolutionized when Anderson and Parrish introduced the theory of selective photothermolysis, promoting the selective destruction of targets in the skin without unwanted surrounding thermal damage. 2 Thereafter, advancements in technology, increased ease of operation, and decreased side effects boosted the popularity of laser therapy for cutaneous disease. Although not inclusive of all skin pathologies amenable to laser therapy, this chapter focuses on the laser treatment for hyperpigmented lesions, benign skin lesions, and basal cell carcinomas (BCCs). AnatomyMelanin, hemoglobin, and water are the three chromophores targeted in skin-directed laser therapy. In normal skin, melanin is produced by melanocytes, transferred to keratinocytes, and confined to the epidermis. Hemoglobin is carried within red blood cells that circulate within blood vessels located in the dermis. Water is present in all layers of the skin but is increased in abundance in the dermis and subcutaneous tissue. Melanin, hemoglobin, and water each exhibit characteristic wavelengths of absorption. Exposure to these energy wavelengths induces excitation to a higher energy state. Lasers with corresponding wavelengths selectively target these chromophores to treat cutaneous pathology while limiting surrounding tissue damage. Hyperpigmented LesionsThe pathogenesis of skin hyperpigmentation is complex. A single or combination of factor(s) such as photosensitivity, trauma, medication deposition, or neoplasia may result in the clinical observation of skin hyperpigmentation. The classification and treatment of pigmentary disorders is based upon the histological location of the pigment within the epidermis, dermis, or a combination of both the epidermis and dermis. Due to melanin's wide spectrum of absorption, several lasers may be used to target this pigment. Ideal laser therapy targets the abnormal pigment without causing surrounding damage. In general, longer wavelength lasers penetrate deeper in the skin. 3 Thus lasers with a shorter wavelength are commonly utilized for superficial pigmented lesions, whereas the longer wavelength lasers are employed for dermal pigmentation.Continuous wave and quasicontinuous wave laser systems were the first laser systems implemented to treat pigmentary disorders. However, the pulse duration of these laser systems is longer than the thermal relaxation time of the melanosome, resulting in significant surrounding thermal damage with subsequent scarring and dyspigmentation. 4 More recently, shortpulsed or quality-switched (QS) lasers ...

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Treatment of Congenital Melanocytic Naevi With CO2 Laser

Cited by 33 publications

References 21 publications

Er:YAG laser resurfacing for inoperable medium-sized facial congenital melanocytic naevi in children

Er:YAG laser resurfacing for inoperable medium-sized facial congenital melanocytic naevi in children

Giant Congenital Melanocytic Nevi

18 The Use of Lasers for Skin Pathology

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