Treatment of chronic migraine with medication overuse: A perspective

Schwedt, Todd J.; Robert, Teri; Dodick, David W.

doi:10.1111/head.14314

Cited by 1 publication

(2 citation statements)

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“…MOH, a fairly common and treatable secondary headache disorder attributed to the overuse of acute headache medications, is underrecognized and produces significant disability and substantial reduction in quality of life. MOH is intimately related to chronic migraine which itself continues to be underrecognized and undertreated 50 . The pathophysiology of MOH involves functional alteration in central pain processing and modulating systems and central sensitization along with psychological and biobehavioral factors.…”

Section: Discussionmentioning

confidence: 99%

“…MOH is intimately related to chronic migraine which itself continues to be underrecognized and undertreated. 50 The pathophysiology of MOH involves Treatment focuses on both the institution of effective preventive migraine therapy and the reduction or removal of the overused medications. Educational efforts directed toward both providers and patients have been shown to be effective in reducing the impact of MOH.…”

Section: Key Pointsmentioning

confidence: 99%

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Medication-Overuse Headache

Rizzoli

2024

CONTINUUM: Lifelong Learning in Neurology

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Objective Medication-overuse headache (MOH) has been described for almost 100 years and is characterized as a daily or near-daily headache that usually presents in patients with preexisting primary headache disorders who are overusing one or more acute or symptomatic headache medications. This article reviews the diagnosis and management of patients with MOH. Latest Developments The International Classification of Headache Disorders criteria for MOH have changed over time. The worldwide prevalence appears to be between 1% and 2%. Together, headache disorders, including MOH, are currently ranked as the second leading cause of years lived with disability in the Global Burden of Disease world health survey. Significant neurophysiologic changes are seen in the brains of patients with MOH, including functional alterations in central pain processing and modulating systems and central sensitization. Research supports updates to the principles of management, including weaning off the overused medication, preventive therapy, biobehavioral therapy, and patient education. Essential Points MOH is a fairly common and treatable secondary headache disorder that produces significant disability and a substantial reduction in quality of life. The costs related to lost income and disability are substantial. MOH is intimately related to chronic migraine, which continues to be underrecognized and undertreated. Treatment focuses on both the institution of effective preventive migraine therapy and the reduction or removal of the overused medications. Educational efforts directed toward both providers and patients have been shown to be effective in reducing the effect of MOH.

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Section: Discussionmentioning

confidence: 99%

Section: Key Pointsmentioning

confidence: 99%