Treatment of breast cancer in elderly patients

Zappulla, E; Russo, Valentina; Gullotta, I; Patanè, Giovanni; Trovato, Salvatore C.; Lucifora, B; Costa, S; Tracia, Angelo; Caglià, Pietro; Amodeo, C

doi:10.1186/1471-2318-9-s1-a57

Cited by 2 publications

(4 citation statements)

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“…While there have been Italian hospital-based studies of cancer outcomes 13,15 , our approach facilitates the study of these quality-of-care indicators for large populations when registry data are unavailable. This approach allows health care managers and medical directors to assess and compare quality of care at a regional level.…”

Section: Discussionmentioning

confidence: 99%

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Using administrative data to identify and stage breast cancer cases: Implications for assessing quality of care

Yuen

Louis

Cisbani

et al. 2011

Tumori

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Cases were identified with good sensitivity, specificity and positive predictive value with SDO data, with better rates than similar previously published algorithms based on Italian data. These hospital claims-based algorithms facilitate quality of care analyses for large populations when registry data are not available by identifying individual women and their subsequent use of health care services.

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Section: Discussionmentioning

confidence: 99%

“…Italian radiotherapy practices and compared these to national and international guidelines 13,14 . Other research on follow-up care has been based in selected oncology units or hospitals, such as a recent single hospital study of chemotherapy and radiation therapies for elderly women 15 .…”

Section: Surveys Of Italian Radiation Oncology Centers Studiedmentioning

confidence: 99%

Using administrative data to identify and stage breast cancer cases: Implications for assessing quality of care

Yuen

Louis

Cisbani

et al. 2011

Tumori

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“…As a consequence, elderly patients cannot be treated in an aggressive way though they are diagnosed at later stages than younger patients [9,19,20]. When assessed from the viewpoint of surgical treatment, it has been reported that a more limited surgical treatment is administered in the elderly and that this situation is much more apparent in patients aged ≥80 years [6].…”

Section: Discussionmentioning

confidence: 99%

“…The situation is similar with radiotherapy and chemotherapy. While in various studies patients aged ≥70 and ≥80 years are emphasized, the consensus is that the patients in this age group receive less chemotherapy and radiotherapy but more hormonal therapy [6,7,19,20]. …”

Section: Discussionmentioning

confidence: 99%

Diagnosis, treatment characteristics, and survival of women with breast cancer aged 65 and above: a hospital-based retrospective study

2013

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BackgroundBreast cancer incidence in women increases with age, while survival rates decrease. Studies interpret this result as meaning higher comorbidity, diagnosis at later stages of the disease, and less effective treatment in the elderly. The aim of this study is to evaluate the diagnosis and treatment characteristics of breast cancer and their effect on the survival of women aged 65 and above.MethodsThe data within the files of 1064 women with breast cancer, who were followed-up in Dokuz Eylul University Medical Faculty Hospital between 2000 and 2006, were reviewed retrospectively. The survival probabilities at years 1 and 5 were calculated by life table analysis. The Kaplan-Meier test was used for calculating mean survival time, and the differences between groups were evaluated by log-rank test. The backward elimination method was used for multivariate analysis, and a −2 log-likelihood ratio was used for comparison of different models.ResultsOf the patients, 25.3% were aged 65 and above at the time of the diagnosis. Patients in this group had more comorbidities and were more likely to be diagnosed at advanced stages than younger patients. Additionally, they had lower rates of surgical treatment, chemotherapy or radiotherapy. One and 5-year survival probabilities among age groups were 96.1% and 84.5%, respectively, for <65 years, 93.5% and 84.8%, respectively, for 65–69, 98.7% and 84.0%, respectively, for 70–74, and 85.5% and 59.6%, respectively, for 75 years and above. In the multivariate model, age, clinical stage, and comorbidity were found to be negatively associated with the survival rate.ConclusionsThe survival of women with breast cancer aged 65 and above was affected negatively by age at diagnosis, clinical stage, and the presence of comorbidity. Early diagnosis also is very important for elderly women. Additionally, because of higher comorbidity, their evaluation and treatment should be planned by an interdisciplinary team.

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Treatment of breast cancer in elderly patients

Cited by 2 publications

References 0 publications

Using administrative data to identify and stage breast cancer cases: Implications for assessing quality of care

Using administrative data to identify and stage breast cancer cases: Implications for assessing quality of care

Diagnosis, treatment characteristics, and survival of women with breast cancer aged 65 and above: a hospital-based retrospective study

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