Treatment of bovine retained placenta and its effects

Peters, A. R.; Laven, Richard

doi:10.1136/vr.139.22.535

Cited by 52 publications

(53 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Activities of some of these enzymes and of their inhibitors are hormone dependent [Salamonsen et al, 1991[Salamonsen et al, , 1993Salamonsen and Nancarrow, 1994;Hampton et al, 1995;. Finally, collagens are a major element of the ovine fetal membranes [Shandley et al, 1997] and the bovine placentome [Sharpe et al, 1990;Sarges et al, 1998], so that the use of collagenase was successfully tested for prevention of retained fetal membranes [Eiler and Hopkins, 1993;Peters and Laven, 1996].…”

Section: Introductionmentioning

confidence: 99%

Immunohistochemical Assessment of Collagen Types I, III, IV and VI in Biopsy Samples of the Bovine Uterine Wall Collected during the Oestrous Cycle

Boos¹

2000

Cells Tissues Organs

View full text Add to dashboard Cite

Uterine biopsies were collected at cycle days 1 (oestrous), 8, 15 and 19 in six cows. Unfixed cryostat sections were used to immunolocalise collagen types I, III, IV and VI by an indirect FITC method. Collagen I was sparsely found in the endometrium where it formed a fine meshwork of thin fibres directly below the surface epithelium, clearly visible only at cycle days 8 and 15. Collagen III formed the bulk of connective tissue fibres and was arranged in fine aggregates within the superficial endometrial stroma, while in the deeper areas it consisted of many thick fibre bundles. Collagen IV was found in basement membranes underlying all endometrial epithelia. Furthermore, it surrounded smooth muscle cells of blood vessels. A few single fibrils also stained positively within the endometrial stroma, more numerous at cycle days 1 and 19 as compared to days 8 and 15. Collagen VI formed a mesh of fine and pericellularly situated fibrils within the endometrial stroma. The contribution of the collagen types studied to the connective tissue of caruncles, blood vessels, lymph follicles, and myometrium is also reported. The results of the present study indicate that the connective tissue of the bovine uterine wall is composed of different collagen types, which exhibit a characteristic distribution pattern each. The day of cycle may influence amounts and organisation of collagen types I and IV as demonstrated here at the light-microscopical level.

show abstract

Section: Introductionmentioning

confidence: 99%

Immunohistochemical Assessment of Collagen Types I, III, IV and VI in Biopsy Samples of the Bovine Uterine Wall Collected during the Oestrous Cycle

Boos¹

2000

Cells Tissues Organs

View full text Add to dashboard Cite

show abstract

“…Concerning RFM, many and different methods of treatment are described with a relative effectiveness, often with contradictory results or with a negative effect on cow's further reproductive performance (Drillich et al, 2007;Frazer, 2005). Manual removal of retained membranes, intrauterine treatment or systemic administration of antibiotics, prostaglandin or estradiol could be mentioned here (Peters & Laven, 1996; Stevens & Dinsmore, 1997; Drillich et al, 2007). In many parts of Europe and less in the United States of America and Canada, veterinarians apply mainly the manual removal of fetal membranes in cows with RFM and administer antibiotics in the uterine cavity .…”

Section: Rfm Treatment Methodsmentioning

confidence: 99%

“…In many parts of Europe and less in the United States of America and Canada, veterinarians apply mainly the manual removal of fetal membranes in cows with RFM and administer antibiotics in the uterine cavity . Some investigations, however, discover that manipulations in the uterine cavity decrease the uterus protective mechanisms (Paisley et al, 1986;Peters & Laven, 1996) and cause infertility (Drillich et al, 2007). Opsomer (2015) had found that cows intrauterine treated with antibiotics did show a reduced incidence of postpartum fever during the first 10 days after calving.…”

Section: Rfm Treatment Methodsmentioning

confidence: 99%

“…Systemic therapy using ceftiofur has given better results in cows with RFM than estradiol and prostaglandin; however, at the same time it has not shown a better reproductive performance in total (Risco & Hermandez, 2003;LeBlanc et al, 2005). Also, immediate administration of prostaglandins, oxytocin or calcium preparations postpartum has not been effective for RFM prevention or faster removal and expel process of fetal membranes (Peters & Laven 1996;LeBlanc et al, 2005). Nevertheless, Santos et al (2002) (Galvão et.al, 2009).…”

Section: Rfm Treatment Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Effects of the Treatment Method of Reproductive Performance in Cows with Retention of Fetal Membranes

Skuja

Antane

2017

Rural Sustainability Research

View full text Add to dashboard Cite

Abstract. The aim of the research was to find out an appropriate method of treatment of retention of fetal membranes (RFM) in cows for conditions of Latvia. Three protocols for the treatment of retained fetal membranes in dairy cows were evaluated in a field trial. Cows that retained the fetal membranes for more than 24 hours were assigned to three treatment groups. Group 1 -control group; group 2 -cows with RFM, which were removed manually, and cows were intrauterine treated with antibiotics; group 3 -cows with RFM, which were not removed, and cows were intrauterine treated with antibiotics, and group 4 -cows with RFM, which were not removed, and cows were not treated. In animals with a decreased feed consumption or milk production, body temperature above 39.5 °C, systemic therapy was applied with ceftiofur hydrochloride or procaine benzilpenicillin. In order to establish subclinical endometritis, all cows were histologically examined on the 42 nd day postpartum (PP). Subclinical mastitis was diagnosed both in cows with RFM and control group cows. Results indicated that better reproductive results were in cows of group 2 and group 4. Actually, results indicated that treatment of RFM without intrauterine manipulation and parenteral treatment could be as effective as conventional treatment including RFM detachment and local antibiotic treatment.

show abstract

“…The absence of any improvement in reproductive performance in Group E and Group DP indicates that there might have been a synergism between estradiol benzoate and dinoprost. Estradiol, in combination with dinoprost, has been shown to reduce intrauterine bacterial contamination [28]. In addition, only Group E+DP received two treatments, and repeated exposure of the uterus to estrogen might have facilitated the clearance of the intrauterine environment.…”

Section: Number Of Ai To Conceptionmentioning

confidence: 99%

The Effect of PGF2α, GnRH, E2 or Antibiotics on the Intrauterine Environment and Reproduction in Holstein Dairy Cows with Retained Placentas

Kaneko¹

2017

J Vet Sci Technol

View full text Add to dashboard Cite

PGF 2α , GnRH, estradiol (E 2 ), or antibiotics were given to dairy cows with retained placenta after parturition to establish the most suitable treatment to prevent the development of endometritis. One hundred and seventy five parous Holstein cows with retained placenta were allocated to into six treatment groups, and groups were given PGF2α, GnRH, E 2 , or antibiotics at 30 or 45 days after parturition. The intrauterine perfusion fluid was collected at 60 days after parturition, and a bacteriological and cytological examination was conducted. Reproductive performance was also investigated. The detection rate for Trueperella pyogenes in the intrauterine perfusion fluid in each group ranged from 0% to 16%, and T. pyogenes was not isolated in cows that were given PGF2α or E 2 . The percentage of neutrophils observed in the intrauterine perfusion fluid ranged from 37.8 ± 5.3 to 56.3 ± 4.7, and it was lowest in cows given PGF2α and highest in cows given GnRH. The mean number of days from parturition to initial insemination, the mean number of days from parturition to conception and the mean number of artificial inseminations required for conception ranged from 85.9 ± 5.5 to 102.7 ± 8.0, 103.8 ± 9.0 to 162.3 ± 18.6 and 1.5 ± 0.2 to 2.6 ± 0.3, respectively. All three parameters were best in cows that were given a combination of PGF2α and E 2 . The results suggest that administration of PGF2α or E 2 , or ideally both, might be a suitable treatment for cows with retained placenta. However, treatment with GnRH might delay the cleansing of the uterus.

show abstract

Treatment of bovine retained placenta and its effects

Cited by 52 publications

References 33 publications

Immunohistochemical Assessment of Collagen Types I, III, IV and VI in Biopsy Samples of the Bovine Uterine Wall Collected during the Oestrous Cycle

Immunohistochemical Assessment of Collagen Types I, III, IV and VI in Biopsy Samples of the Bovine Uterine Wall Collected during the Oestrous Cycle

Effects of the Treatment Method of Reproductive Performance in Cows with Retention of Fetal Membranes

The Effect of PGF2α, GnRH, E2 or Antibiotics on the Intrauterine Environment and Reproduction in Holstein Dairy Cows with Retained Placentas

Contact Info

Product

Resources

About