Treatment of benign and low-grade malignant intramedullary chondroid tumours with curettage and cryosurgery

Schreuder, H.W.B.; Pruszczyński, M; Veth, R.P.H.; Lemmens, J.A.M.

doi:10.1016/s0748-7983(98)91459-7

Cited by 98 publications

(71 citation statements)

References 24 publications

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“…The mean, median, and mode MSTS functional scores of the 39 subjects from whom MSTS scores were obtained were 27.2, 29, and 30, respectively, of 30 points (Fig. 3) (SD 4.8; range, [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30].…”

Section: Resultsmentioning

confidence: 99%

Curettage and Cryosurgery for Low-grade Cartilage Tumors Is Associated with Low Recurrence and High Function

Mohler

Chiu

McCall

et al. 2010

Clinical Orthopaedics &Amp; Related Research

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Background Chondrosarcomas of bone traditionally have been treated by wide or radical excision, procedures that may result in considerable lifelong disability. Grade 1 chondrosarcomas have little or no metastatic potential and are often difficult to distinguish from painful benign enchondromas. Curettage with adjuvant cryosurgery has been proposed as an alternative therapy for Grade 1 chondrosarcomas given the generally better function after the procedure. However, because it is an intralesional procedure, curettage and cryosurgery may be associated with higher rates of recurrence. Questions/purposes We asked whether Grade 1 chondrosarcomas and enchondromas of uncertain malignant potential treated by curettage and cryosurgery are associated with low recurrence rates and high functional scores. Patients and Methods We retrospectively reviewed the records of 46 patients with Grade 1 chondrosarcomas and enchondromas of uncertain malignant potential treated by curettage and cryosurgery. Forty-one patients had tumors of the long bones. Patients were followed a minimum of 18 months (average, 47.2. months; range, 18-134 months) for evidence of recurrence and for assessment of Musculoskeletal Tumor Society (MSTS) functional score.

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Section: Resultsmentioning

confidence: 99%

Curettage and Cryosurgery for Low-grade Cartilage Tumors Is Associated with Low Recurrence and High Function

Mohler

Chiu

McCall

et al. 2010

Clinical Orthopaedics &Amp; Related Research

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“…In this series, parietal sterilization was achieved with a simplified cryotherapy technique based on that described by Marcove et al [18]. We did not use an injector or a temperature probe as described in other series [1,28], but this did not seem to compromise the ability to destroy the tumor. This technique seemed as effective as others (Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…Each author certifies that his or her institution has approved the reporting of these cases, that all investigations were conducted in conformity with ethical principles of research, and that informed consent was obtained. intralesional treatment of these low-grade chondrosarcomas combining tumor excision with skeletal conservation [1,14,18,19,24,28]. After curettage alone, Bauer et al noted two cases of recurrence among 23 patients with chondrosarcomas [2].…”

Section: Introductionmentioning

confidence: 99%

No Recurrences in Selected Patients after Curettage with Cryotherapy for Grade I Chondrosarcomas

Souna

Belot

Duval

et al. 2010

Clinical Orthopaedics &Amp; Related Research

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Background The low aggressiveness of Grade I chondrosarcomas is compatible with conservative surgical treatment. Questions/purpose We asked whether combined curettage and cryotherapy would yield low rates of recurrence and whether supplemental internal fixation would retain function with low rates of complications in patients with Grade I central chondrosarcomas of the proximal humerus or distal femur. Methods We retrospectively reviewed 15 patients: nine women and six men with a mean age of 45 years (range, 26-70 years). All patients underwent curettage and cryosurgery through a cortical window; we replaced the window and plated the region with at least three screws beyond the curetted area. None of the patients was lost to followup, and 14 patients (93%) were reexamined by us after a minimum of 5 years (mean, 8 years; range, 5-11 years). Results There were no perioperative anesthetic, neurologic, hardware, or healing complications. None of the patients had local recurrence or metastases develop. At last followup, the Musculoskeletal Tumor Society score was 27.9 (range, 22-30) and all patients had resumed their previous activities. No complications were associated with this simplified cryotherapy technique. Conclusions The data confirm the appropriateness of conservative surgery for central low-grade chondrosarcomas of the proximal humerus and distal femur based on a combination of intralesional curettage and cryogenic parietal sterilization. Candidates for this approach should be chosen on the basis of the affected bone site, local extension staging, and clinicopathologic grading. We recommend supplementary internal fixation.

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“…Intralesional curettage, either alone or combined with local adjuvant treatments, marginal resection, and en bloc resection with biologic or endoprosthetic reconstruction are all described in the literature [5,13,19,21,22,22,23,24,25].…”

Section: Discussionmentioning

confidence: 99%

“…Some authors advocate wide excision, necessitating substantial reconstructive surgery, often requiring massive endoprostheses or allografts [21,22]. In contrast, many others believe that less extensive surgery is indicated for less aggressive lesions [5,13,19,23,24,25]. This would minimises the need for complex limb reconstruction and results in a good functional outcome.…”

Section: A C C E P T E D Article In Pressmentioning

confidence: 99%

Outcome of intralesional curettage for low-grade chondrosarcoma of long bones

Hanna

Whittingham-Jones

Sewell

et al. 2009

European Journal of Surgical Oncology (EJSO)

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Treatment of benign and low-grade malignant intramedullary chondroid tumours with curettage and cryosurgery

Cited by 98 publications

References 24 publications

Curettage and Cryosurgery for Low-grade Cartilage Tumors Is Associated with Low Recurrence and High Function

Curettage and Cryosurgery for Low-grade Cartilage Tumors Is Associated with Low Recurrence and High Function

No Recurrences in Selected Patients after Curettage with Cryotherapy for Grade I Chondrosarcomas

Outcome of intralesional curettage for low-grade chondrosarcoma of long bones

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