Treatment of basal cell carcinoma with surgical excision and perilesional interferon-α

Wettstein, Reto; Erba, Paolo; Itin, Peter; Schaefer, Dirk J.; Kalbermatten, Daniel F.

doi:10.1016/j.bjps.2013.03.008

Cited by 8 publications

(2 citation statements)

References 36 publications

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“…Combination therapy. There were few studies, and of very low certainty, evaluating a number of different combination therapies to treat nodular BCC, such as combinations of diclofenac + calcitriol, 121 imiquimod + Mohs micrographic surgery, 122,123 interferon-a + standard surgical excision, 124 topical PDT + Mohs micrographic surgery 125 and lasers + topical PDT. [126][127][128] In order to assess such combination therapies, they need to be followed up for at least 5 years.…”

Section: Other Treatmentsmentioning

confidence: 99%

British Association of Dermatologists guidelines for the management of adults with basal cell carcinoma 2021*

et al. 2021

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Section: Other Treatmentsmentioning

confidence: 99%

British Association of Dermatologists guidelines for the management of adults with basal cell carcinoma 2021*

et al. 2021

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“…ese combinations include diclofenac with calcitriol, imiquimod and MMS, interferon-α and standard surgical excision, topical PDT and MMS, and lasers and topical PDT. [52][53][54][55][56][57][58][59]…”

Section: Immunotherapymentioning

confidence: 99%

Treatment of basal cell carcinoma: An overview

Bali

Deif

Rajeev

2022

JSSTD

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Basal cell carcinoma (BCC) is the most common cutaneous cancer worldwide, but accounts for only 2–4% of skin cancers in Asian population. Tumor characteristics such as size, location, pathology, and risk of recurrence, as well as treatment tolerability, cost, and patient preference influence the selection of treatment. The goal of treatment is complete tumor removal in superficial/locally invasive BCCs and prolongation of survival in the rare setting of metastatic BCC. Various treatment options available include conventional surgical excision, Mohs micrographic surgery, cryosurgery, electrodesiccation and curettage, topical application of imiquimod or 5-fluorouracil, and photodynamic, and radiotherapy. Surgical excision and Mohs surgery are preferred because of low recurrence rate and the possibility to evaluate the clearance through histology. In the treatment of metastatic or locally advanced lesions, hedgehog pathway inhibitors and the recently approved drug cemiplimab can be beneficial. Sun protection and regular skin self-checks are recommended for all patients with BCC. This literature review gives an overview of the treatment of BCC.

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