Treatment of Atrial Fibrillation Using Ablation Index-Guided Contact Force Ablation: A Matching-Adjusted Indirect Comparison to Cryoballoon Ablation

Abstract

Introduction: Ablation Index, also known as VISITAG SURPOINT TM , is a novel lesion-quality marker that improves outcomes in radiofrequency (RF) catheter ablation of atrial fibrillation (AF). There is no direct evidence on the comparative effectiveness of RF ablation with Ablation Index and cryoballoon (CB). The

Effectiveness of Radiofrequency Catheter Ablation Using Ablation Index Versus Second Generation Cryoballoon in the Treatment of Persistent Atrial Fibrillation: A Matching-Adjusted Indirect Comparison

“…An unanchored MAIC was conducted between the pooled STAI IPD and the pooled CB cohorts because of a lack of a common comparator between studies. MAIC analyses were conducted using methods outlined by Phillippo et al [11], and detailed methods have been previously described [13]. Briefly, IPD from the STAI studies were matched to the CB studies by removing STAI patients who would have not met the eligibility criteria of the CB studies.…”