1996
DOI: 10.1159/000171546
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Treatment of Ascites: Old and New Remedies

Abstract: Ascites is a common complication of chronic liver disease. Treatment of the underlying liver disease with modalities such as abstinence from alcohol in Laennec’s cirrhosis, phlebotomy in hemochromatosis, copper removal in Wilson’s disease, and steroids in autoimmune liver disease, can improve survival in many patients. In addition, therapy of ascites alleviates the symptoms and improves the quality of life of the patients, and probably decreases the incidence of life-threatening conditions including spontaneou… Show more

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Cited by 7 publications
(4 citation statements)
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References 47 publications
(60 reference statements)
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“…Patients with RA usually have additional complications, including spontaneous bacterial peritonitis, hepatorenal syndrome and hepatic hydrothorax (3–4). Large volume paracentesis (LVP), a transjugular intrahepatic portosystemic shunt (TIPS), peritoneovenous shunts and portocaval shunts have all been used (1–9) in treating patients with RA. Liver transplantation (LT) is the best therapeutic option for patients with end‐stage liver disease and ascites, because the ascites usually disappears after LT. Ascites after LT has been reported, and its occurrence has been associated with hepatic vein outflow obstruction (10–12).…”
Section: Introductionmentioning
confidence: 99%
“…Patients with RA usually have additional complications, including spontaneous bacterial peritonitis, hepatorenal syndrome and hepatic hydrothorax (3–4). Large volume paracentesis (LVP), a transjugular intrahepatic portosystemic shunt (TIPS), peritoneovenous shunts and portocaval shunts have all been used (1–9) in treating patients with RA. Liver transplantation (LT) is the best therapeutic option for patients with end‐stage liver disease and ascites, because the ascites usually disappears after LT. Ascites after LT has been reported, and its occurrence has been associated with hepatic vein outflow obstruction (10–12).…”
Section: Introductionmentioning
confidence: 99%
“…Peritoneovenous shunt devices were developed in order to permit the continuous reinfusion of the ascitic fluid [3]. Because of the surgical approach needed, the implantation of these devices requires a careful selection of the patients, taking into account their prognosis and the possible real benefit which can be obtained by the shunt.…”
Section: Discussionmentioning
confidence: 99%
“…The ideal treatment should aim to control the symptomatology and improve quality of life, with the least patient discomfort. The treatments commonly used, such as fluid restriction with diuretics, repeated paracenteses, intracavitary and external beam radiotherapy, systemic or intraperitoneal chemotherapy, and immunotherapy, all allow symptom palliation with poor, temporary, and generally unsatisfactory results [1,2,3,4].…”
Section: Introductionmentioning
confidence: 99%
“…According to some reports, the insertion of this type of shunt is associated with a subclinical disseminated intravascular coagulation in all patients and can cause thrombophlebitis and clinically significant disseminated intravascular coagulation in 5 to 10 per cent of patients, which requires removal of the device. 2,3 Furthermore, a high percentage of patients have a postoperative course complicated by sepsis and thromboembolic events. 4,5 More patients could become free from the problems associated with tense ascites if a device could be implanted in the abdomen with the ascitic fluid shunted into the bladder.…”
mentioning
confidence: 99%