Treatment of Arterial Occlusive Disease of the Lower Extremities

Whittemore, Anthony D.; Couch, Nathan P.; Mannick, John A.

doi:10.1146/annurev.me.36.020185.002445

Cited by 5 publications

References 26 publications

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Mechanical properties of the aneurysmal aorta

MacSweeney

Young

Greenhalgh

et al. 1992

British Journal of Surgery

107

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The mechanical properties of the abdominal aorta were investigated non-invasively in 30 patients with aortic aneurysm and 11 with peripheral arterial disease. The distensibility of the aorta was measured using M-mode ultrasonography, permitting non-invasive assessment of the pressure--strain elastic modulus or aortic stiffness, Ep. The median Ep value increased from 4.0 N/cm2 in control subjects in their third decade of life (n = 10) to 10.4 N/cm2 in middle age (n = 11) to 14.0 N/cm2 in the elderly (n = 13). In the presence of a normal diameter, peripheral arterial disease with aortic atherosclerosis had little effect on aortic stiffness, median Ep being 16.0 N/cm2. Aneurysmal dilatation was associated with a significant increase in aortic stiffness, median Ep being 31.3 N/cm2 (P < 0.001). For aortas of normal diameter, Ep was at all ages dependent on mean arterial pressure. In patients with aortic aneurysms there was no clear relationship between Ep and mean arterial pressure or aortic diameter. Of the patients studied, 15 underwent aortic reconstruction; increasing aortic stiffness (log Ep) was associated with a decreased medial elastin content of the aortic biopsy (r = -0.63, P < 0.02). This study demonstrates the marked stiffness or inelasticity of dilated or aneurysmal vessels, part of which is attributable to the loss of elastin.

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Mechanical properties of the aneurysmal aorta

MacSweeney

Young

Greenhalgh

et al. 1992

British Journal of Surgery

107

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Smoking

Powell¹

1991

Epidemiology of Peripheral Vascular Disease

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Evolution and current use of technology for superficial femoral and popliteal artery interventions for claudication

Schneider

2017

Journal of Vascular Surgery

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An important facet in caring for patients with claudication is the development of a plan for managing the technology available for superficial femoral artery (SFA) and popliteal artery interventions. Although this is a field in evolution, clinical experience and data are emerging that assist the clinician in making informed choices as to the best method of endovascular treatment. Algorithms for SFA and popliteal artery interventions are developing. Methods for assessing a wide range of technologies are discussed. This article reviews the evolution of technology for SFA and popliteal artery interventions, describes the recent developments in data and clinical experiences, and discusses some potential methods of device assessment and incorporation into clinical practice.

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Treatment of Arterial Occlusive Disease of the Lower Extremities

Cited by 5 publications

References 26 publications

Mechanical properties of the aneurysmal aorta

Mechanical properties of the aneurysmal aorta

Smoking

Evolution and current use of technology for superficial femoral and popliteal artery interventions for claudication

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