“…11,12,20,24 Several veterinary publications have reported successful radiographic periodontal bone regeneration using the bioglass product b without a membrane although the results were not confirmed histologically. 1,[25][26][27] Results of a recent human clinical study suggest that there is increased inhibition of epithelial apical migration using membranes compared with bioactive glass alone. 28 Additionally, a human literature meta-analysis concluded that membranes in general, when combined with any type of bone graft, result in greater clinical attachment levels.…”