Treatment of Allergic Rhinitis during Pregnancy

Keleş, Nesil

doi:10.1177/194589240401800106

Cited by 49 publications

(31 citation statements)

References 39 publications

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“…Rhinitis affects at least 20% of pregnancies [154] and can start during any gestational week [155]. Although the pathogenesis is multifactorial, nasal vascular engorgement and placental growth hormone are likely to be involved [155,156].…”

Section: Rhinitis and Pregnancymentioning

confidence: 99%

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BSACI guidelines for the management of allergic and non‐allergic rhinitis

Scadding

Durham

Mirakian

et al. 2007

Clin Experimental Allergy

348

292

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SummaryThis guidance for the management of patients with allergic and non-allergic rhinitis has been prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI). The guideline is based on evidence as well as on expert opinion and is for use by both adult physicians and paediatricians practicing in allergy. The recommendations are evidence graded. During the development of these guidelines, all BSACI members were included in the consultation process using a web-based system. Their comments and suggestions were carefully considered by the SOCC. Where evidence was lacking, consensus was reached by the experts on the committee. Included in this guideline are clinical classification of rhinitis, aetiology, diagnosis, investigations and management including subcutaneous and sublingual immunotherapy. There are also special sections for children, co-morbid associations and pregnancy. Finally, we have made recommendations for potential areas of future research.

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Section: Rhinitis and Pregnancymentioning

confidence: 99%

“…Patients already on immunotherapy may continue if they have already reached the maintenance phase but each case must be considered individually. However, initiation of immunotherapy and updosing is contraindicated [154].…”

Section: Rhinitis and Pregnancymentioning

confidence: 99%

BSACI guidelines for the management of allergic and non‐allergic rhinitis

Scadding

Durham

Mirakian

et al. 2007

Clin Experimental Allergy

348

292

View full text Add to dashboard Cite

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“…Pharmacological treatment is often necessary. The most commonly used medications are antihistamines and corticosteroids [11, 12]. In this context, a less extensively investigated but simple alternative is the use of nasal rinsing with isotonic or hypertonic solutions.…”

Section: Introductionmentioning

confidence: 99%

“…The management of allergic rhinitis includes allergen avoidance, pharmacological treatment and specific immunotherapy [10, 11]. While measures aimed to remove allergen exposure have first to be considered, this may not be always effective, particularly for outdoor allergens.…”

Section: Introductionmentioning

confidence: 99%

Nasal Lavage in Pregnant Women with Seasonal Allergic Rhinitis: A Randomized Study

Garavello

Somigliana

Acaia

et al. 2009

Int Arch Allergy Immunol

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Background: Nasal rinsing appears particularly suitable in the management of pregnant women with seasonal allergic rhinitis since no deleterious effects on the fetus are to be expected. However, to date, no studies have specifically investigated this option. Methods: Pregnant women with seasonal allergic rhinitis were randomized to intranasal lavage with hypertonic saline solution 3 times daily (n = 22) versus no local therapy (n = 23) during a 6-week period corresponding to the pollen season. Patients were invited to keep a daily record of rhinitis symptoms (rhinorrea, obstruction, nasal itching and sneezing), to record consumption of oral antihistamine and to undergo rhinomanometry. Results: The rhinitis score was similar at study entry but a statistically significant improvement in this score was observed in the study group during all subsequent weeks (p < 0.001 for weeks 2–6). The mean number of daily antihistamines use per patient per week was significantly reduced at weeks 2, 3 and 6 (p < 0.001, p < 0.001 and p = 0.001, respectively). Baseline rhinomanometry performed at week 1 showed similar nasal resistance in the study and control groups. In contrast, a statistically significant difference emerged in the 2 following evaluations. At week 3, nasal resistance in the study and control groups was 0.96 ± 0.44 and 1.38 ± 0.52 Pa/ml/s, respectively (p = 0.006). At week 6, it was 0.94 ± 0.38 and 1.35 ± 0.60 Pa/ml/s, respectively (p = 0.006). No adverse effect was reported in the active group. Conclusions: Nasal rinsing is a safe and effective treatment option in pregnant women with seasonal allergic rhinitis.

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“…A stepwise approach is always recommended (Figure 2) [53,54]. It is important to consider that, in the presence of persistent rhinitis (as defined by the Allergic Rhinitis and its Impact on Athsma [ARIA] document), the possible presence of concomitant asthma should be carefully investigated.…”

Section: Pregnancy Rhinitismentioning

confidence: 99%

Allergic Rhinitis in Women

Passalacqua

2007

Womens Health (Lond Engl)

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Allergic rhinitis is a high-prevalence disease that significantly impairs the quality of life. Its pathogenesis is quite well understood, and involves numerous cells, cytokines and mediators, which result in an inflammatory process. The triggering IgE-mediated reaction does not differ between men and women, but in females some aspects, related mainly to the hormonal frame, must be taken into account. In fact, cyclic hormonal changes can affect the severity of rhinitis, as can pregnancy, which may result in a particular form of ‘pregnancy rhinitis’. The most important and challenging aspect is the management of allergic rhinitis in pregnancy, which require a careful evaluation of the risk:benefit ratio. This review will examine the aforementioned aspects, with particular regard to the pharmacotherapy of rhinitis in pregnancy.

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Treatment of Allergic Rhinitis during Pregnancy

Cited by 49 publications

References 39 publications

BSACI guidelines for the management of allergic and non‐allergic rhinitis

BSACI guidelines for the management of allergic and non‐allergic rhinitis

Nasal Lavage in Pregnant Women with Seasonal Allergic Rhinitis: A Randomized Study

Allergic Rhinitis in Women

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