Treatment of Adult Varicella with Oral Acyclovir

Abstract

Early therapy with oral acyclovir decreases the time to cutaneous healing of adult varicella, decreases the duration of fever, and lessens symptoms. Initiation of therapy after the first day of illness is of no value in uncomplicated cases of adult varicella. The low frequency of serious complications of varicella (pneumonia, encephalitis, or death) precluded any evaluation of the possible effect of acyclovir on these outcomes.

Varicella zoster virus infection

“…6). In immunocompetent patients, oral acyclovir, or preferably famciclovir, or valaciclovir need to be started within 24 h of the first skin lesions to shorten the duration of fever and rash 173 ; 5 days and 7 days of treatment have comparable efficacy 174 .…”

Evaluation Of Hospitalized Herpes Zoster Cases

“…Yapılan bir epidemiyolojik çalışmada 50 yaş üstü olgularda %10-20, 80 yaş üstü olgularda %30 oranında PHN saptanmıştır (28). Ağrının şiddetinin ve süresinin de yaşla birlikte arttığı gösterilmiştir (29 …”

Neumonía varicelosa en adultos: 30 casos

“…Afecta solamente al 1-2% de los adultos (2). Representando este segmento de población menos del 5% de las varicelas pero más de un tercio de los fallecidos (3).…”