2003
DOI: 10.1192/bjp.182.44.s15
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Treatment models for those with severe mental illness and comorbid personality disorder

Abstract: BackgroundDual diagnosis of personality disorder and severe mental illness is an important clinical association that has been under-researched with regard to clinical management.AimsTo compare the outcomes of differenttreatment models.MethodThe outcome of patients with this combined diagnosis was compared in a systematic review of three randomised controlled trials in which different forms of community outreach treatment or intensive case management were compared with standard care.ResultsThe results from the … Show more

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Cited by 54 publications
(41 citation statements)
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References 19 publications
(19 reference statements)
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“…People with personality disorders have fewer attachment and support figures in the community than do others (Tyrer et al, 1994), and few community teams can provide the level of support and treatment needed when function begins to disintegrate. The findings of differential outcomes have been replicated in three randomised trials with over 900 patients (Tyrer & Simmonds, 2003) and cannot be lightly ignored.…”
Section: Box 4 Engagement and Maintenance In Treatmentmentioning
confidence: 54%
“…People with personality disorders have fewer attachment and support figures in the community than do others (Tyrer et al, 1994), and few community teams can provide the level of support and treatment needed when function begins to disintegrate. The findings of differential outcomes have been replicated in three randomised trials with over 900 patients (Tyrer & Simmonds, 2003) and cannot be lightly ignored.…”
Section: Box 4 Engagement and Maintenance In Treatmentmentioning
confidence: 54%
“…Tyrer and Simmonds [7] reviewed the outcome of three randomised controlled trials that investigated different models of care in SMI, and found in post-hoc analyses that patients with co-morbid PD spent more time in hospital compared to those without co-morbid PD, regardless of the model of care. Keown and others investigated psychiatric bed use amongst SMI patients seen in a UK community mental health team, and found that the concurrent presence of PD and also severity of PD were associated with increased psychiatric bed use amongst SMI patients [7][6]. Our finding that co-morbid PD increases inpatient service use in SMI patients is consistent with existing evidence that co-morbid personality pathology worsens outcomes in SMI [24] [27].…”
Section: Previous Work and Possible Mechanismsmentioning
confidence: 99%
“…Patients with SMI and co-morbid PD are likely to require tailored interventions that target both the underlying personality pathology as well as the Axis I disorder. In this respect, better treatment models are required to help to reduce admissions and involuntary hospitalization for patients with SMI and comorbid Axis II pathology [7][41] [44].…”
Section: Strengths and Limitationsmentioning
confidence: 99%
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“…A systematic literature review of outpatient treatment for individuals with psychosis and PD identified only 2 satisfactory UK trials-early community intervention, compared with hospitalization, and community-focused care, compared with standard care. 161 Comorbid groups fared worse in the community. In the United States, using the MacArthur study 75 multisite risk study cohort, patient perceptions of their treatment need, treatment adherence, and treatment effectiveness were each associated with reduced odds of violence during 6 months as outpatients.…”
Section: Treatment Modelsmentioning
confidence: 99%