Treatment Modalities of Complex Regional Pain Syndrome After Hand Surgery a Systematic Review and Meta-Analysis Study

Abstract

Background: complex regional pain syndrome is a complex medical condition. Physical/occupational treatments, psychiatric counseling, neuropathic pain medicines, anti-inflammatories, and surgical intervention are utilized to treat complex regional pain syndrome (CRPS). Aim of the study: The aim of this work is to do meta-analysis study of complex regional pain syndrome treatment modalities after hand surgery in most recent literatures. Patients and Methods: After full-text screening 12papers were included in this systemic review and meta-analysis.This research was conducted and reported following PRISMA (for systematic review and metaanalysis recommended reporting items). From 2016 to 2021. Results: 10 studies showed Responders with a high event in bisphosphonate than in Ketamine study with highly significant heterogeneity among included studies p-value 0.0005. 12 studies were included 6 studies showed adverse events with highly significant heterogeneity p-value <0.0001. Conclusion:Although there has yet to be good therapy for CRPS, years of study have taught us a lot about the disorder and our knowledge of it is still growing. Furthermore, in comparison to CRPS type I, the evidentiary foundation for CRPS type II is limited. As a result, further research is required to determine which patient subgroups might benefit the most from presently available treatments. Because of the syndrome's complexity, focusing on a single mechanism is unlikely to be beneficial. Therapy combination, like with other chronic disorders, maybe the future of CRPS management, and research into this will be required.