Treatment-induced neuropathy of diabetes: an underdiagnosed entity

Treatment‐induced neuropathy of diabetes: an update

“…33 Although the evidence does not point toward relaxing glycaemic control aiming to accelerate pain resolution, the current consensus states that good glycaemic control must not be relaxed. 12,16,42,43 Neuropathic pain in patients with TIND may progressively alleviate in a few weeks or in up to 36 months; 30,41 however, it is necessary to start analgesic therapy to reduce pain. 10,[48][49][50] In some cases, TIND pain is much more severe than that of DN, so singleagent therapy may be maximised, or a second or a third drug may be added to analgesic therapy.…”

“…During the years after its first description, few TIND cases were reported; however, its presence in the medical literature has increased in the last decades 12 (Appendix ), indicating that this condition would be more frequent than it was initially thought 13 . Its prevalence in subjects with diabetes in a third‐level reference centre was reported to be 10.9% 13 …”

“…Since the main reason for visiting a physician is neuropathic pain, the main objective of the therapy is pain management; therefore, the same drugs prescribed for DN may be used 33 . Although the evidence does not point toward relaxing glycaemic control aiming to accelerate pain resolution, the current consensus states that good glycaemic control must not be relaxed 12,16,42,43 …”