Treatment Guidelines for Community-acquired Pneumonia in Korea: An Evidence-based Approach to Appropriate Antimicrobial Therapy

Song, Jae-Hoon; Jung, Kyomin; Kang, Moon Won; Kim, Dojin; Pai, Hyunjoo; Suh, Gee Young; Shim, Tae Sun; Ahn, Joong Hyun; Ahn, Chul Min; Woo, Jun Hee; Lee, Nam Yong; Lee, Dong Gun; Lee, Mi Suk; Lee, Sang Moo; Lee, Yeong Seon; Lee, Hyukmin; Chung, Doo Ryeon

doi:10.3947/ic.2009.41.3.133

Cited by 28 publications

(42 citation statements)

References 96 publications

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“…Regarding empirical antibiotics, all except one patient treated with macrolide alone received guideline-concordant therapy according to the treatment guidelines for CAP in Korea. 30 β-Lactam was prescribed in 1397 (92%) patients including 726 patients with antipseudomonal β-lactam. Combination therapy with either macrolide (48%) or fluoroquinolone (41%) was common.…”

Section: Resultsmentioning

confidence: 99%

Functional status and mortality prediction in community‐acquired pneumonia

et al. 2017

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Section: Resultsmentioning

confidence: 99%

Functional status and mortality prediction in community‐acquired pneumonia

et al. 2017

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“…All patients were treated with antibiotics according to local practice guidelines. 24 Clinical parameters for analysis included demographic and clinical characteristics, comorbid medical conditions, 25 pneumonia treatment, antimicrobial susceptibility, and treatment outcome. The PSI 22 and CURB-65 26 scores were calculated based on the clinical presentation of pneumonia.…”

Section: Definitions and Data Collectionmentioning

confidence: 99%

Impact of preceding respiratory viral infections on the clinical severity of patients with pneumococcal pneumonia

Yoon

Yang

Lee

2014

Influenza Resp Viruses

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BackgroundThis study aimed to investigate the impact of preceding respiratory viral infections (RVI) on the clinical severity of pneumococcal pneumonia patients.MethodsA retrospective observational study was conducted at a university hospital from January 2009 to March 2013. Study subjects included adults (aged ≥18 years) with pneumococcal pneumonia who had undergone laboratory tests for RVI. Multivariate logistic regression analysis was performed to identify risk factors associated with severe pneumococcal pneumonia, defined as severity with the Pneumonia Severity Index (PSI) score ≥91.ResultsIn total, 191 patients with pneumococcal pneumonia were included for analysis and stratified into 2 groups: the severe group with a PSI score ≥91 (n = 99) and the non-severe group with a PSI score <91 (n = 92). Preceding RVIs were detected in 48 patients, including influenza A virus (n = 20), influenza B virus (n = 4), parainfluenza viruses (n = 5), metapneumovirus (n = 4), rhinovirus (n = 4), respiratory syncytial viruses (n = 6), coronaviruses (n = 2), and mixed viral infections (n = 3). In the multivariate logistic regression analysis, preceding RVIs (odds ratio [OR], 2·49; 95% confidence interval [CI], 1·10–5·60), male sex (OR, 2·58; 95% CI, 1·24–5·38), old age (OR, 2·92; 95% CI, 1·37–6·24), hypoalbuminemia (OR, 3·26; 95% CI, 1·56–6·84)], and azotemia (OR, 2·24; 95% CI, 1·08–4·67) were significantly associated with severe pneumococcal pneumonia.ConclusionThis study suggests that preceding RVIs might be one of the risk factors affecting the clinical severity of pneumococcal pneumonia.

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“…The clinical manifestations of pneumonia caused by L. monocytogenes are similar to those of pneumonia caused by other organisms [19]. Some recommendations for empiric pneumonia therapy include the use of cephalosporins [20]. Such antibiotic regimens will not be effective against L. monocytogenes.…”

Section: Discussionmentioning

confidence: 99%