Treatment-free remission after discontinuation of tyrosine kinase inhibitors in patients with chronic myeloid leukemia in the chronic phase: a systematic review and meta-analysis
Zhenxiang Zheng,
Hao Tang,
Xinxia Zhang
et al.
Abstract:BACKGROUND: Treatment-free remission (TFR) is a new long-term goal for the treatment of patients with chronic myeloid leukemia (CML), but the appropriate group in which TFR can be attempted and the factors influencing it have not yet been identified. This meta-analysis aimed to explore TFR in chronic myeloid leukemia chronic phase (CML-CP) patients who achieved a deep molecular response (DMR) before Tyrosine kinase inhibitors (TKIs) discontinuation and to explore possible factors influencing TFR and the safety… Show more
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