Treatment for peritoneal dialysis-associated peritonitis

Abstract

Analysis 1.2. Comparison 1 Intravenous (IV) versus intraperitoneal (IP) antibiotics, Outcome 2 Adverse events.. . Analysis 1.3. Comparison 1 Intravenous (IV) versus intraperitoneal (IP) antibiotics, Outcome 3 Infusion pain.. . Analysis 2.1. Comparison 2 Oral (drug A) versus intraperitoneal (drug A) antibiotics (same antibiotic), Outcome

Difficult peritonitis cases in children undergoing chronic peritoneal dialysis: relapsing, repeat, recurrent and zoonotic episodes

“…Catheter removal Catheter exchange is another treatment option and has been shown to be superior to urokinase in lowering treatment failure rates in relapsing or persistent peritonitis [29,30]. Removal of the PD catheter is indicated as soon as peritonitis is controlled by antibiotic therapy in the setting of relapsing peritonitis associated with a persistent or recurrent tunnel infection, or when there is a second peritonitis relapse (Table 2) [12].…”

“…Removal of the PD catheter is indicated as soon as peritonitis is controlled by antibiotic therapy in the setting of relapsing peritonitis associated with a persistent or recurrent tunnel infection, or when there is a second peritonitis relapse (Table 2) [12]. In most cases, simultaneous removal and replacement of the PD catheter is permissible and prevents the need for temporary HD [12,30].…”

Peritoneal dialysis practice in Australia and New Zealand: A call to sustain the action

“…Aim(s) ANZDATA KPI Project 2,3 Provide valid, correctable markers that are easy to understand and implement focussed on HD and PD access Baxter Healthcare PD Academy Improve the quality of life and maximize the quality of care of PD patients, promote a philosophy of integrated care among renal clinicians, give confidence to those managing or starting a PD programme and develop future leaders in PD Cochrane Systematic Review on Peritonitis 4 Provides updated evidence-based evaluation of benefits and harms of treatments for PD-associated peritonitis KHA-CARI Guideline Implementation Project 5,6 Two-phase project focussed on ensuring implementation of KHA-CARI and ISPD guidelines regarding the prophylactic use of antibiotics and antifungals in PD patients using baseline data collection and tools to overcome barriers Peritoneal Dialysis Outcomes and Practice Patterns Study 7,8 Increase the appropriate use of PD, extend technique survival and improve quality of life for PD patients through greater understanding of modifiable management practices on the risk of all-cause peritoneal dialysis technique failure Queensland Health Clinical Pathways Project 9 Provide pathways for paediatric and adult patients presenting with clinical peritonitis, covering assessment, empiric treatment and post-culture treatment and referral Renal Health Clinical Network KPI Project 10 Provide KPIs that cover definitions, inclusions/exclusions, data submission and reporting, and targets (includes CKD education and peritonitis rates) Royal Hobart Hospital Exit Site Care Quality Improvement Activity 11 Develop a continuous quality improvement programme to establish a more structured approach to the existing exit site care plan (led to dramatic actual reductions in exit site infection rates) Victorian Continuous Quality Improvement Program 12 Support service providers to monitor and continuously improve their service coordination implementation and practice based on a continuous quality improvement framework ANZDATA, Australia and New Zealand Dialysis and Transplant Registry; CARI, Caring for Australasians with Renal Impairment; CKD, chronic kidney disease; HD, haemodialysis; ISPD, International Society for Peritoneal Dialysis; KHA, Kidney Health Australia; KPI, key performance indicators; PD, peritoneal dialysis.…”

Evidence-based medicine: An update on treatments for peritoneal dialysis-related peritonitis

“…Wiggins et al [17] [18] , from the same group of investigators, published an update of this systematic review. The authors included RCTs and quasi-RCTs to assess the treatment of peritonitis in adults and children.…”

“…Most of these excluded studies were case series. In turn, their authors have noted the inclusion of many trials with small patient numbers as a limitation [17,18] . In an attempt to overcome these limitations, our center is employing an alternative methodology: the proportional meta-analysis to examine possible differences among therapeutic protocols.…”