Treatment for Mycobacterium abscessus Infection Associated with Fat Grafting

Abstract

Background: Fat grafting is a standard method for soft augmentation. However, occasionally Mycobacterium abscessus infection can be seen secondary to fat grafting. The aim of this study was to report experience with and propose standard treatment. Patients and Methods: From 2006 to 2018, 12 women who had received fat grafting for facial soft augmentation in different Chinese private clinics were reviewed. Results: The patients presented with local swelling and skin ulceration. They patients received primary infusion of antibiotic agents; however, the results were poor. After being admitted to our hospital, cultures were taken and sent to the specialized examination center. Mycobacterium abscessus was diagnosed in all of the patients. According to drug sensitivity results, targeted antibiotic agent treatment was implemented for 12 months. Local proper conservative debridement was conducted as needed. When the patients were discharged from the hospital, they were advised to continual oral medication for six months. After three to nine years of follow-up, no recurrence was found. On the basis of this, a corresponding standard treatment was proposed. Conclusions: Mycobacterium abscessus infection after fat grafting should be diagnosed and treated accurately. Our experience and proposed treatment may be beneficial.

Prolonged antibiotic prophylaxis in tissue reconstruction using autologous fat grafting: Is there a benefit for wound healing?

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Nontuberculosis Mycobacteria Infection After Liposuction and Fat Grafting for Augmentation Mammoplasty

“…[4][5][6]8,9 Drug resistance is very common, and no optimal antibiotic regimen has yet been proposed. However, successful treatment was still achieved in the majority of recent studies 4,[6][7][8]16 by a combination of surgical debridement and multiantibiotics treatment.…”

Fat Augmentation as Adjunct to CORE Facelift Surgery

“…24 In the series (n ¼ 12) described by Chen, fever was the presenting symptom, followed by granulomatous skin abscesses and tissue loss. 31,32 The diagnosis is commonly initially overlooked.…”