Treatment for diabetic ulcer wounds using a fern tannin optimized hydrogel formulation with antibacterial and antioxidative properties

Versatile Hyperbranched Poly(β-hydrazide ester) Macromers as Injectable Antioxidative Hydrogels

“…Several hydrogel systems incorporated with free-radical scavenging motifs have been reported and showed significantly enhanced antioxidative property. [11][12][13][14] However, some key challenges persist regarding the optimal formulation of antioxidative hydrogels, such as complicated synthetic procedures, hazardous reagents, limited and unsuitable mechanical properties, and inefficient antioxidation, leading to restricted clinical and failure of specific applications. 15 Poly(β-amino ester)s (PBAEs), first reported by Robert Langer and co-workers, 16,17 have been widely used in the field of gene delivery [18][19][20] and tissue scaffold applications 21,22 due to their excellent biodegradability and biocompatibility.…”

Estudos químico e biológico de taninos e antraquinonas que atuam no sistema gastrointestinal

“…Thus, considering that histopathological studies have proven epithelization, fibroblast proliferation, and angiogenesis by tannins in healed wound tissues, these molecules act in more mechanisms than just physical barrier (LAI et al, 2016). In the present work we observed the gastroprotective barrier formed by tannins.…”

Tannins: Prospectives and Actual Industrial Applications

“…This is due to their complexation ability with other molecules and their antioxidant behavior. The extract of Stryphnodendron rotundifolium and of other tannins has proven their effectiveness against ulcers by functioning as a protective coating of the gastrointestinal tract [57,58,59]. Other possible mechanisms of action of phenolic plant extracts as herbal medicines against ulcers and gastritis have also been described [57,58,59,60].…”