Treatment for COVID-19—a cohort study from Northern Italy

Guglielmetti, Lorenzo; Aschieri, Daniela; Kontsevaya, Irina; Calabrese, Francesco; Donisi, Alessandra; Faggi, Alberto; Ferrante, Patrizia; Fronti, Elisa; Gerna, Laura; Leoni, Maria Cristina; Paolillo, F; Ratti, Giovanna; Sacchini, D.; Scotti, Marta; Valdatta, Caterina; Stabile, Marco; Taliani, Gloria; Codeluppi, Mauro

doi:10.1038/s41598-021-00243-4

Cited by 2 publications

(3 citation statements)

References 4 publications

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“…The findings from the large RECOVERY trial confirmed several previous studies that found modest or no benefit in azithromycin use in patients admitted to hospital with COVID-19 [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ].…”

Section: Resultssupporting

confidence: 81%

“…Two-hundred-forty-five studies were excluded for not reporting data on antibiotic use in COVID-19 patients. From the remaining 118 studies, 36 studies were included in this systematic review ( Figure 1 ) [ 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 ].…”

Section: Resultsmentioning

confidence: 99%

“…Of the 36 studies included in the systematic review, 32 studies were on the use of antibiotics in COVID-19 inpatients [ 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]; 4 reported on antibiotic use in COVID-19 outpatients [ 37 , 38 , 39 , 40 ].…”

Section: Resultsmentioning

confidence: 99%

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Antibiotics Use in COVID-19 Patients: A Systematic Literature Review

Granata

Schiavone

Pipitone

et al. 2022

JCM

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The issue of bacterial infections in COVID-19 patients has received increasing attention among scientists. Antibiotics were widely prescribed during the early phase of the pandemic. We performed a literature review to assess the reasons, evidence and practices on the use of antibiotics in COVID-19 in- and outpatients. Published articles providing data on antibiotics use in COVID-19 patients were identified through computerized literature searches on the MEDLINE and SCOPUS databases. Searching the MEDLINE database, the following search terms were adopted: ((antibiotic) AND (COVID-19)). Searching the SCOPUS database, the following search terms were used: ((antibiotic treatment) AND (COVID-19)). The risk of bias in the included studies was not assessed. Both quantitative and qualitative information were summarized by means of textual descriptions. Five-hundred-ninety-three studies were identified, published from January 2020 to 30 October 2022. Thirty-six studies were included in this systematic review. Of the 36 included studies, 32 studies were on the use of antibiotics in COVID-19 inpatients and 4 on antibiotic use in COVID-19 outpatients. Apart from the studies identified and included in the review, the main recommendations on antibiotic treatment from 5 guidelines for the clinical management of COVID-19 were also summarized in a separate paragraph. Antibiotics should not be prescribed during COVID-19 unless there is a strong clinical suspicion of bacterial coinfection or superinfection.

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