“…99,100 Multiple studies have documented the loss of micronutrients, such as copper, zinc, selenium, folic acid, magnesium, vitamin C, vitamin E, thiamin, chromium, and iron. [98][99][100][101][102] In one study of patients undergoing CVVHD, different dialysis doses did not result in clinically relevant losses of folic acid, vitamin B 12 , zinc, magnesium, and inorganic phosphate. 100 This study specifically involved CVVHD and not other types of CRRT, so this may not be generalizable across all CRRT modalities.…”