“…Ferakis et al [30 ] investigated the treatment characteristics of the Prostalund device in relation to clinical efficacy parameters in 48 patients of which 28 had an indwelling catheter, but neither the intraprostatic temperatures, the duration of this temperature in the therapeutic range, the bloodflow pattern, nor the treatment duration or the magnitude of tissue necrosis matched the clinical response. In the nonretention group, however, it appeared that the combination of time, temperature and maintenance of intraprostatic temperatures for a longer time are indicators for a clinical response.…”