Treatment approaches in small bronchi inflammatory control in bronchial asthma patients

Abstract

This article reviews the significance of distal airways inflammation in asthma, current methods of investigations and therapeutic approaches to control inflammation at the level of small bronchi. It is demonstrated that inflammation in most asthma patients involves all airways including the small bronchi. The new drugs targeting distal airways, including extrafine formulations of inhaled steroids and P2-agonists (beclomethazone/formoterol (Fostair), can successfully treat pathologic process in small bronchi of asthma patients.