Treatment and rehabilitation for cervical cancer: the experience of patient journey management

Akavova, A. A.; Solopova, A. G.; Blinov, D. V.; Achkasov, E. E.; Galkin, V. N.; Korabelnikov, D. I.; Mnatsakanyan, A. N.; Petrenko, D. A.; Bykovshchenko, G. K.; Khazan, P. L.

doi:10.17749/2313-7347/ob.gyn.rep.2023.461

Akušerstvo, ginekologiâ i reprodukciâ

2023

DOI: 10.17749/2313-7347/ob.gyn.rep.2023.461

|View full text |Cite

Treatment and rehabilitation for cervical cancer: the experience of patient journey management

A. A. Akavova,

A. G. Solopova,

D. V. Blinov

et al.

Abstract: Radical surgical intervention, chemoradiotherapy and immune therapy implicated for patients with cervical cancer (CC) can result in significant morphofunctional, psychological, sexual disorders and social maladjustment. To optimize treatment and rehabilitation for CC patients, a routing approach has been established. This approach involves the patient's journey during diagnosis and treatment with well-defined timed stages. Additionally, a rehabilitation program with lifelong follow-up has been implemented. Pri… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

The effectiveness of rehabilitation in vulvovaginal atrophy

Ampilogova,

Solopova,

Blinov

et al. 2024

Farmakoèkonomika

View full text Add to dashboard Cite

Objective: to evaluate the effectiveness and safety of rehabilitation programmes in patients with vulvovaginal atrophy (VVA).Material and methods. The study involved 350 patients with VVA in surgical (n=140) and natural (n=140) menopause, the control group included 70 women without VVA. Patients with VVA were distributed into groups receiving complex “active” rehabilitation (surgical menopause: group 1A, natural menopause: group 2A) and “passive” rehabilitation (surgical menopause: group 1B, natural menopause: group 2B). Body mass index (BMI), vaginal pH, carbohydrate profile with calculation of insulin resistance index (HOMA-IR), inflammatory markers leptin, interleukin-6, tumour necrosis factor alpha, serum magnesium, and safety profile with evaluation of adverse events related to rehabilitation measures were assessed over 24 months.Results. BMI decreased significantly in groups 1A and 2A. Vaginal pH at 1-year follow-up decreased in groups 1A and 2A, but increased in groups 2A and 2B. BMI was higher than normal in all patients with VVA, as well as in the control group, demonstrating preobesity (groups 1A, 2A, control group) or first-degree obesity (initially in group 1B and throughout follow-up in group 2B). HOMA-IR initially reflected postoperative insulin resistance in groups 1A and 2A, but in those receiving complex “active” rehabilitation the dynamics of its reduction was the most pronounced. The concentration of inflammatory markers was initially increased compared to the control group and decreased over time in groups 1A and 1B, but only leptin levels reached the control group values by the end of the study. Serum concentration of magnesium levels was 0.71±0.12 mmol/l in group 1A, 0.71±0.10 mmol/l in group 2A, 0.76±0.08 mmol/l in group 1B, 0.72±0.17 mmol/l in group 2B (magnesium deficiency). When organic magnesium salts in combination with pyridoxine were supplemented in groups 1A and 1B, serum magnesium levels were restored to normal from the 3rd month of follow-up. No adverse events were registered.Conclusion. The personalised programme of complex “active” rehabilitation in patients with VVA is more effective than “passive” rehabilitation with comparable safety profile. Its implementation into routine practice will contribute to the improvement of the quality of health care for such patients.

show abstract

The effectiveness of rehabilitation in vulvovaginal atrophy

Ampilogova,

Solopova,

Blinov

et al. 2024

Farmakoèkonomika

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Treatment and rehabilitation for cervical cancer: the experience of patient journey management

Cited by 1 publication

References 44 publications

The effectiveness of rehabilitation in vulvovaginal atrophy

The effectiveness of rehabilitation in vulvovaginal atrophy

Contact Info

Product

Resources

About