Treatment and recurrence in giant cell tumour locally advanced around the knee

Abstract

Background-Giant cell tumour (GCT) is a benign bone tumour with aggressive characteristics. They are more prevalent in the third decade of life and demonstrate a preference for locating in the epiphyseal region of long bones. They have a high local recurrence rate, which depends on the type of treatment and initial tumour presentation. Objective- To evaluate the results of the treatment with regard to relapse. Methods- It was a hospital based follow up study done for periods of 7 months. Fifty patients of GCT were recruited in the study through purposive sampling technique.Study being conducted on patients with followup for 12 months. Demographic profile and all the necessary investigation were done. SPSS ( Version 22.0) was used for analysis. Chi-Square test was used as test of significance. Results-There was a predominance of males (80%). The most common location was the distal femur. All patients presented with pathologic fracture at diagnosis, recurrence seen after 9months of followup.the most common location for GCT was distal femur seen in 84% of patients, while curettage with cement was the most common treatment done in 89% which was statistically significant (p<0.05). Endoprosthesis was done in 11% patient.