Treatment and Prognosis of Chondroblastoma

Lin, Patrick P.; Thenappan, Arun; Deavers, Michael T.; Lewis, Valerae O.; Yasko, Alan W.

doi:10.1097/01.blo.0000179591.72844.c3

Cited by 131 publications

(155 citation statements)

References 9 publications

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“…We did not observe any clinically relevant growth arrest, limb length discrepancies, or malalignments as complications. Many authors have reported that tumors in the proximal femur and the pelvis are more likely to recur as a result of the difficulty in the surgical access necessary to achieve complete excision [15,18,22,24]. We have described only one proximal femur recurrence after performing a direct anterior or anterolateral approach in most cases.…”

Section: Discussionmentioning

confidence: 75%

What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty

Farfalli

Slullitel

Múscolo

et al. 2017

Clinical Orthopaedics &Amp; Related Research

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Section: Discussionmentioning

confidence: 75%

What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty

Farfalli

Slullitel

Múscolo

et al. 2017

Clinical Orthopaedics &Amp; Related Research

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“…However, of eight cases with functional impairment at follow-up, five involved the hip, with the other three all at different sites [1]. Lin et al noted that few patients with chondroblastoma had much growth remaining, but that four patients who had treatment before skeletal maturity had a growth plate disturbance [13]. They also reported that all patients with femoral head chondroblastomas were curetted by a cortical window in the femoral neck, but none developed avascular necrosis.…”

Section: Discussionmentioning

confidence: 97%

“…Radiotherapy is contraindicated, as there is a significant risk of inducing a malignant transformation. Recurrence rates of 10-40% have been described [1,5,9,13]. There have been rare reports of seeding into soft tissues locally, and of pulmonary metastasis in about 1% of cases [12,14].…”

Section: Discussionmentioning

confidence: 98%

Chondroblastoma of the femoral head: management and outcome

Strong

Grimer

Carter

et al. 2009

International Orthopaedics (SICOT)

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Chondroblastoma of the femoral head presents particular problems in treatment because the tumour is surrounded by articular cartilage on one side and epiphyseal plate on the other. Ten patients underwent treatment for a chondroblastoma involving the proximal femoral capital epiphysis. The patients were aged between eight and 19 years and in four the epiphysis was not yet fused. Five had curettage via a drill hole created up the femoral neck, of whom two developed local recurrence. Five had a direct approach to the chondroblastoma through the femoral neck, and there were no local recurrences in this group. Both patients with local recurrence were under 14 years of ageone was cured by a direct approach through the neck of the femur and the other by lifting a trap door of articular cartilage. Apart from one patient with a temporary leg length discrepancy, there were no other complications. We conclude that a direct approach is likely to lead to the best outcome for this rare condition.

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“…Chondroblastoma is an uncommon benign bone tumour, which is locally aggressive [1][2][3][4], and arises from a secondary ossification centre in epiphyseal plates and apophyses [5][6][7]. Chondroblastoma accounts for approximately 1-2 % of all primary bone tumours [8].…”

Section: Introductionmentioning

confidence: 99%

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

Mashhour

Rahman

2013

International Orthopaedics (SICOT)

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Purpose Various methods for the treatment of chondroblastoma of bone have been used including simple curettage, or combined with bone grafting, in addition to the use of adjuvant therapy. However, local recurrence still represents a challenge in the management of this aggressive tumour. This study focuses on evaluating the role of intraregional extended curettage together with the use of adjuvant cryotherapy and autogenous bone grafting in the treatment of benign chondroblastoma of bone aiming to decrease the recurrence rate. Methods All patients with chondroblastoma included in this study underwent intralesional extended curettage, adjuvant cryotherapy using liquid nitrogen, and autogenous iliac crest bone grafting. Follow up for healing of chondroblastoma lesions and detection of any local recurrence was assessed on clinical and radiological bases. The functional outcome was assessed by the Musculoskeletal Tumour Society scoring system. Results The mean follow-up period was 49 months. The average time for bone healing was 7.4 months. Our rate of local recurrence is 7.1 %. Two patients (14.3 %) developed physeal growth arrest. One patient had superficial skin sloughing (7.1 %). None of the cases had pathological fracture. The mean Musculoskeletal Tumour Society functional score was 92.7 %. Conclusion Chondroblastoma is an aggressive benign bone tumour with a high rate of recurrence. The use of high-speed burr combined with adjuvant intralesional cryotherapy and iliac crest autogenous bone grafting is a reliable method of treatment with a low rate of recurrence.

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Treatment and Prognosis of Chondroblastoma

Abstract: Therapeutic Study, Level IV (case series). See the Guidelines for Authors for a complete description of levels of evidence.

Cited by 131 publications

References 9 publications

What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty

What Happens to the Articular Surface After Curettage for Epiphyseal Chondroblastoma? A Report on Functional Results, Arthritis, and Arthroplasty

Chondroblastoma of the femoral head: management and outcome

Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery

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