“…The direct transposition of recommendations derived from studies on heart failure from other aetiologies in patients generally from Europe and North America to Latin American Chagas disease patients is potentially misleading (Botoni et al 2007b). Moreover, the physician's perception that Chagas disease is a distinct condition may lead to suboptimal dosing or a lack of initiation of medications with proven efficacy in patients with other heart failure aetiologies (Botoni et al 2007a). Thus, validated recommendations for the management of Chagas-associated heart failure are clearly needed.…”