Treating bipolar disorder in patients with renal failure having haemodialysis: two case reports

Gupta, Maneesh; Annadatha, Srinivas

doi:10.1186/1745-0179-4-21

Cited by 5 publications

(2 citation statements)

References 8 publications

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“…Contrary to this, in our study renal nurses probed patients with SMI to ascertain if they were in pain or feeling unwell due to infection and referred patients accordingly for medical treatment. Potential reasons for fluctuating mental capacity in patients with SMI receiving haemodialysis may be attributed to uraemia, infection and non-adherence with psychiatric medication (Gupta and Annadatha, 2008). This suggests that renal nurses may have more resilience than other nurses caring for patients with SMI due to their regular and on-going contact with patients.…”

Section: Discussionmentioning

confidence: 99%

Renal nurses' experiences of patients with severe mental health conditions receiving acute haemodialysis: A qualitative study

Alwar

Addis

2021

Journal of Renal Care

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Background Patients receiving acute haemodialysis treatment and living with severe mental illness may display behaviours that are perceived as challenging and stressful for renal nurses to manage in the acute haemodialysis unit. Renal nurses are historically trained on the technical aspects of acute haemodialysis and can provide a level of psychological support to patients. However, they have not been trained to manage patients with severe mental illness. Objective To explore renal nurses' experiences of nursing patients with severe mental illness receiving acute haemodialysis, and to identify factors that facilitate or hinder the nursing care of these patients. Design A descriptive qualitative study. Method Purposive sampling was employed, and semi‐structured interviews were conducted with 10 renal nurses working in an acute haemodialysis unit. Thematic analysis was utilised to analyse the data. Findings Thematic analysis identified four main themes which are perspectives of mental Illness, patient and staff safety concerns, facilitators of care and education and support needs. Conclusion Renal nurses experienced difficulty managing challenging behaviours manifested by patients with severe mental illness. Despite the various challenges, renal nurses adopted a person‐centred approach. Staff shortages and lack of training were significant hindrances to care delivery. Education on mental health conditions, support from senior staff and collaborative working can enable confidence and increase renal nurses' knowledge and experience in mental health care.

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Section: Discussionmentioning

confidence: 99%

Renal nurses' experiences of patients with severe mental health conditions receiving acute haemodialysis: A qualitative study

Alwar

Addis

2021

Journal of Renal Care

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“…VPA is primarily metabolized by the liver; therefore, the management of the dose and blood level should be relatively easy because of its low dialyzability [ 15 ]. Therefore, VPA seems to be safe even for patients on hemodialysis.…”

Section: Case Presentationmentioning

confidence: 99%

Development of acute pancreatitis caused by sodium valproate in a patient with bipolar disorder on hemodialysis for chronic renal failure: a case report

et al. 2014

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BackgroundCases of acute pancreatitis caused by sodium valproate (VPA) have been reported by many authors thus far. However, most of these were cases with epilepsy. Chronic renal failure is also regarded as a risk factor for acute pancreatitis. Here, we report a case of acute pancreatitis development due to VPA in a patient with bipolar disorder on hemodialysis for chronic renal failure.Case presentationThe patient was a 52-year-old Japanese male who was diagnosed as bipolar disorder on hemodialysis for renal failure. He was treated with VPA and manic symptoms gradually stabilized. However, the patient complained of severe abdominal pain. Blood amylase was found to be markedly high, and computed tomography revealed pancreatomegaly and an increased amount of peripancreatic fat. Hence, we diagnosed the case as acute pancreatitis caused by VPA. We discontinued oral medication, and he was started on a pancreatic enzyme inhibitor, antibiotics, and transfusion, and he showed improvement.ConclusionIt has been reported that acute pancreatitis induced by VPA is caused by intermediate metabolites of VPA. We consider that patients with renal failure are prone to pancreatitis caused by VPA because of the accumulation of these intermediate metabolites. We need close monitoring for serious adverse effects such as pancreatitis when we prescribe VPA to patients with bipolar disorder on hemodialysis for chronic renal failure, although VPA is safer than other mood stabilizers.

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Antipsychotic Treatment in a Patient With Schizophrenia Undergoing Hemodialysis

Batalla

Vera

Torra

et al. 2010

Journal of Clinical Psychopharmacology

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Treating bipolar disorder in patients with renal failure having haemodialysis: two case reports

Cited by 5 publications

References 8 publications

Renal nurses' experiences of patients with severe mental health conditions receiving acute haemodialysis: A qualitative study

Renal nurses' experiences of patients with severe mental health conditions receiving acute haemodialysis: A qualitative study

Development of acute pancreatitis caused by sodium valproate in a patient with bipolar disorder on hemodialysis for chronic renal failure: a case report

Antipsychotic Treatment in a Patient With Schizophrenia Undergoing Hemodialysis

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