Treating amyotrophic lateral sclerosis with allogeneic Schwann cell–derived exosomal vesicles: a case report
Pascal J. Goldschmidt-Clermont,
Aisha Khan,
George Jimsheleishvili
et al.
Abstract:Schwann cells are essential for the maintenance and function of motor neurons, axonal networks, and the neuromuscular junction. In amyotrophic lateral sclerosis, where motor neuron function is progressively lost, Schwann cell function may also be impaired. Recently, important signaling and potential trophic activities of Schwann cell-derived exosomal vesicles have been reported. This case report describes the treatment of a patient with advanced amyotrophic lateral sclerosis using serial intravenous infusions … Show more
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