Treadmill exercise and neuroinflammation

Real, Caroline Cristiano; Binda, Karina Henrique; Landau, Anne M

doi:10.1016/b978-0-12-817990-1.00034-2

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The Influence Of Physical Exercise On Redox Balance In Aging and Brain Diseases1

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2021

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“…Additionally, lack of PA, overeating and sleep disturbances can promote neurodegeneration. These are agents that favor brain aging, as well as mental or neurological diseases [ 100 , 101 ]. As early as 65 years ago, Dr. Denham Harman showed ROS as a source of aging in his free radical theory of aging [ 102 ].…”

Section: The Influence Of Physical Exercise On Redox Balance In Aging and Brain Diseasesmentioning

confidence: 99%

Physical Activity vs. Redox Balance in the Brain: Brain Health, Aging and Diseases

et al. 2021

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It has been proven that physical exercise improves cognitive function and memory, has an analgesic and antidepressant effect, and delays the aging of the brain and the development of diseases, including neurodegenerative disorders. There are even attempts to use physical activity in the treatment of mental diseases. The course of most diseases is strictly associated with oxidative stress, which can be prevented or alleviated with regular exercise. It has been proven that physical exercise helps to maintain the oxidant–antioxidant balance. In this review, we present the current knowledge on redox balance in the organism and the consequences of its disruption, while focusing mainly on the brain. Furthermore, we discuss the impact of physical activity on aging and brain diseases, and present current recommendations and directions for further research in this area.

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Section: The Influence Of Physical Exercise On Redox Balance In Aging and Brain Diseasesmentioning

confidence: 99%