Treacherous fantasy: The unfulfilled promise of Kt/V

Beat von Albertini: Lifetime search for increased dialysis treatment efficiency—An obituary

“…6 During the following decades, the idea of reducing dialysis treatment time by simply increasing the physical performance of the dialyzer became obsolete and was controversially discussed, based on observed long-term complications. 7,8 With the advent of high-volume hemodiafiltration with substitution volumes of more than 20 L while using high-flux dialyzers and high blood flows, the original ideas of Beat von Albertini received a late confirmation. Due to a better patient survival with high substitution volume as the new term for “dialysis dose,” this technology is currently gaining more and more acceptance in the nephrological community.…”