“…Stiffness is a clinically relevant symptom reported by patients and has implications for patient-relevant health outcomes in the rehabilitation setting. In the initial evaluation of patients presenting with spinal stiffness, consideration should be given to the possibility of serious causes such as inflammatory disease, 2,141 degenerative conditions, 173,175 infection (bacterial or viral), 160,268 cancer, 152 trauma, 4,155,156 intracranial pathology, 162,171 and postoperative complications. [129][130][131][132][133] The symptom of stiffness and its relationship to other clinical manifestations is essential to differentiate between a benign condition and pathophysiology.…”