Trauma und PTBS in jugendlichen Patienten mit einer Substanzkonsumstörung

Basedow, LA; Kuitunen‐Paul, Sören; Roessner, P; Golub, Yulia

doi:10.1055/s-0039-1696292

Cited by 1 publication

(4 citation statements)

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“…Prevalence data on MA use (in comparison to MUD diagnosis) and from samples comprising both adolescents and adults are presented in the main text. A preliminary analysis of the dataset for PTSD prevalence 143 with N = 79 and 31% prevalence rate had been submitted for poster presentation before the literature search was conducted in July 2019. In order to provide the best available estimate, we decided to include the prevalence rate of 28% based on the full data set 93 although it was published in 2020 after the initial literature search. C-DIS IV: Computer-assisted Diagnostic Interview Schedule for DSM-IV; 178 DUDIT: Drug Use Disorders Identification Test; 179 GHQ—12 = General Health Questionnaire Version 12; 180 K-SADS-E: Epidemiological Version of Kiddy Schedule for Affective Disorders and Schizophrenia; 181 N.A.…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Most of the prevalence studies examined samples with rather specific substance use patterns, e.g., suburban Australian MA users, 9 imprisoned Taiwanese adolescents with MUD, 51 or German outpatients with MUD and other SUDs. 143 The vast range of assessment instruments may furthermore account for varying prevalence rates. Instruments ranged from screening questionnaires to structured diagnostic interviews assessing mental disorders.…”

Section: Limitationsmentioning

confidence: 99%

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Beyond the Tip of the Iceberg: A Narrative Review to Identify Research Gaps on Comorbid Psychiatric Disorders in Adolescents with Methamphetamine use Disorder or Chronic Methamphetamine Use

et al. 2021

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Background Methamphetamine use disorder (MUD) frequently begins in adolescence, often accompanied by other psychiatric or mental disorders. Up to now, no comprehensive review about MUD and comorbid disorders in adolescents is available. We thus aimed to review the literature on comorbid mental disorders and MUD in adolescents in order to identify future research topics. Method A PubMed search was conducted in July 2019. Relevant comorbidities were defined as attention-deficit disorder with/without hyperactivity, anxiety disorders, depression, eating disorders, post-traumatic stress disorder, psychosis, borderline personality disorder, conduct disorder and antisocial personality disorder, as well as other substance use disorders. For each comorbidity, we summarized prevalence rates, findings on comorbidity mechanisms, and recommended treatment options, if applicable. Results Few articles focused on MUD in adolescents. Prevalence rates differed largely between comorbid disorders, with tobacco use disorder, conduct disorder, post-traumatic stress disorder, anxiety disorders, and attention-deficit disorders being the most prevalent comorbidities while eating disorders were rare. Examined onset patterns and comorbidity mechanisms indicated three groups of comorbidities: preexisting disorders self-medicated with methamphetamine, disorders induced by chronic methamphetamine use, and disorders arising due to risk factors shared with MUD. Reviewed comorbidities were frequently associated with worse treatment outcomes. Conclusions The limited evidence is in stark contrast to the presumably high prevalence and relevance of comorbid mental disorders in adolescents with MUD. Suggestions for future research topics, informed by adult findings, include genetic vulnerabilities, biological changes, and consequences of different use patterns. Surprisingly few MUD treatment programs explicitly integrate comorbid mental disorder modules.

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