Trauma-induced focal nodular mucinoses: A rare entity

Gr, Verma; Mrig, Pooja A; Gautam, R. K.; Malhotra, Purnima

doi:10.4103/idoj.idoj_63_17

Cited by 5 publications

(5 citation statements)

References 8 publications

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“…The diagnosis of trauma‐induced cutaneous mucinosis is based upon the history and the clinico‐pathologic correlation. In two patients, cutaneous focal mucinosis developed on the mammary areola, respectively after a laser‐based epilation of hairs and a piercing procedure, while blunt trauma was a trigger in another case 33–34 . Another patient developed cutaneous focal mucinosis after ear piercing procedure (personal observation; Fig.…”

Section: Resultsmentioning

confidence: 99%

“…25 Cutaneous mucinoses following physical agents including mechanical traumas and after knee replacement Although UV-radiation has been implicated in exacerbating some types of mucinosis, 1 the role of physical agents including mechanical traumas in the development of cutaneous mucinosis has been recently outlined. [33][34] The clinical presentation is polymorphous, and while some lesions could be classified as wellknown entities, such as cutaneous focal mucinosis, other lesions could not fit a precise nosology and have been simply called "cutaneous mucinosis", mainly due to histopathologic findings. [33][34] The microscopic features were either those of a dermal mucinosis or those of a follicular mucinosis.…”

Section: Differential Diagnosismentioning

confidence: 99%

“…[33][34] The clinical presentation is polymorphous, and while some lesions could be classified as wellknown entities, such as cutaneous focal mucinosis, other lesions could not fit a precise nosology and have been simply called "cutaneous mucinosis", mainly due to histopathologic findings. [33][34] The microscopic features were either those of a dermal mucinosis or those of a follicular mucinosis. [35][36] In this setting, also, the cases of cutaneous mucinosis developing adjacent to replaced joints can be included.…”

Section: Differential Diagnosismentioning

confidence: 99%

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New and emerging conditions of acquired cutaneous mucinoses in adults

Rongioletti

2022

Acad Dermatol Venereol

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Cutaneous mucinoses are a heterogenous group of conditions, characterized by the deposition of glycosaminoglycans (mucin) in the dermis, follicles, or in the epidermis. Major cutaneous mucinoses include lichen myxedematosus, scleredema, mucinoses associated with thyroid disease, reticular erythematous mucinosis, papulonodular mucinosis associated with connective tissue diseases, and cutaneous focal mucinosis. The aim of this review is to provide an update of what has currently been reported in the last 30‐year literature about several new or emerging conditions of acquired cutaneous mucinoses in adults. Two new clinico‐pathologic entities have been described: (i) Obesity‐associated lymphedematous mucinosis and pretibial stasis mucinosis; (OACM) (ii) Nodular mucinosis of the breast (NMB). Two relatively new disease categories encompassing cutaneous mucinoses with a common pathogenetic mechanism have been identified: (i) Cutaneous mucinoses associated with drug exposure including biologic therapy, anti–colony‐stimulating factor 1 receptor (CSF1R) and subcutaneous intralesional interferons (toxic dermal mucinoses); (ii) Cutaneous mucinosis following physical agents including mechanical traumas and after knee replacement.

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Section: Resultsmentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

Section: Differential Diagnosismentioning

confidence: 99%

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New and emerging conditions of acquired cutaneous mucinoses in adults

Rongioletti

2022

Acad Dermatol Venereol

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“…However, both of our patients lacked any indications of friction, trauma, or rubbing, and neither reported a history of such incidents. 12,13 As for pediatric age, the main differential diagnosis is with self-healing juvenile cutaneous mucinosis. The diagnostic criteria that are helpful to favor a diagnosis of self-healing juvenile cutaneous mucinoses include an acute onset of symptoms with a typical distribution of cutaneous lesions characterized by deep nodules on the face and periarticular regions in addition to mucinous papules, followed by spontaneous resolution.…”

Section: Discussionmentioning

confidence: 99%

“…However, both of our patients lacked any indications of friction, trauma, or rubbing, and neither reported a history of such incidents. 12,13…”

Section: Discussionmentioning

confidence: 99%

Nodular-Type Lichen Myxedematosus: A Rare Variant With Exclusive Involvement of the Hands—Report of Two Cases With a Comprehensive Review of the Literature

Cerroni,

Rongioletti

2024

The American Journal of Dermatopathology

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Lichen myxedematosus (LM) is an uncommon cutaneous mucinosis characterized by the deposition of mucin and fibroblast proliferation in the dermis. This condition can be classified into 2 forms: a diffuse/generalized LM, also known as scleromyxedema, associated with monoclonal gammopathy and systemic implications, and a localized form, primarily affecting the skin. Within the localized form, nodular-type LM is a rare variant presenting as firm, skin-colored to pinkish mucinous nodules. In this article, we report 2 new cases of nodular-type LM with exclusive involvement of the hands and provide a comprehensive review of the diagnosis, histopathological aspects, and therapeutic considerations of this rare condition.

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