Tratamiento del cáncer de laringe avanzado y calidad de vida. Revisión sistemática

García-León, Francisco Javier; García-Estepa, Raúl; Romero-Tabares, A.; Borrachina, Jaime Gómez-Millán

doi:10.1016/j.otorri.2016.11.005

Cited by 23 publications

(9 citation statements)

References 20 publications

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“…Surgical resection remains the preferred treatment because of LSCC is insensitive to currently used chemotherapeutics. Despite improvements in operative and diagnostic technique, the long-term overall survival is still dissatisfactory [4][5][6]. The postoperative adjuvant treatment including radiotherapy or chemoradiotherapy is used to decrease recurrence and improve the long-term survival.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, surgical resection has been become the preferred treatment for LSCC. In the past 20 years, although there have been advances in term of diagnosis and treatment, it has not been satisfactory in the long-term survival for LSCC patients [4][5][6]. The postoperative regimens combining chemotherapy and radiation are increasingly being used to decrease radical radiotherapy-induced complication and prolong survival.…”

Section: Introductionmentioning

confidence: 99%

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Prognostic Significance of Lymph Node Metastases and Ratio in Laryngeal Squamous Cell Carcinoma

Wang¹,

Li²,

Lü³

et al. 2020

Preprint

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Background The lymph node metastases (LNM) and the lymph node ratio (LNR) were shown to be prognostic factors in head and neck cancer. The purpose of this study was to investigate the prognostic significance of the LNM and LNR in patients with laryngeal squamous cell carcinoma (LSCC). Methods All patients undergoing resection of laryngeal cancer at the First Affiliated Hospital of Chongqing Medical University between March 2011 and December 2018 were reviewed. Univariate and multivariate analyses were performed using log-rank and Cox proportional hazard models, and survival curves estimated using the Kaplan-Meier method. Results Of 670 patients with LSCC, the median overall survival (OS) of was 42.2 months, and 3-year and 5-year OS rates were respectively 92.9 ± 1.1% and 86.1 ± 1.7%. 12.69% (85/670) were pathological nodal positive (pN+). LNM was associated with tumor site, T stage and differentiation degree (p < 0.05). And the 5-year OS rates in the pathological nodal negative (pN-) and pN + groups were 88.7± 1.7% and 69.9 ± 5.9%, respectively (p = 0.000), and the presence of pN + was the most significant prognostic factor for survival. Furthermore, the 5-year OS of patients with 1 to 3 positive LN and 4 or more positive LN were 64.6±8.1% and 44.9 ± 15.2%, respectively (p = 0.032). Additionally, LNR examination did not reach significance in our study. However, it demonstrates that increasing LNR was associated with worsening survival. Conclusion LNM is an independent prognostic factor in LSCC, and increasing number of positive LN and LNR in patients portend a poor prognosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prognostic Significance of Lymph Node Metastases and Ratio in Laryngeal Squamous Cell Carcinoma

Wang¹,

Li²,

Lü³

et al. 2020

Preprint

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“…La fibrosis inducida por radiación da como resultado atrofia muscular, lo que contribuye a la disminución de la función de deglutoria, y provoca en el paciente dificultades con el transporte adecuado de alimentos, lo que puede conducir a residuos y aspiración 10,11 .…”

Section: Reporte De Casos Clínicosunclassified

Abordaje fisioterapéutico en las alteraciones funcionales producidas por la cirugía del cáncer de amígdalas palatinas: reporte de caso

Pérez¹,

Vargas

2019

Rev Ter

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La rehabilitación oncológica es dirigida a aquellos pacientes con un diagnóstico de cáncer, el cual deriva discapacidad debido a la cirugía, la quimioterapia y la radioterapia. El reporte de caso corresponde a un paciente masculino, de 63 años de edad, diagnosticado en 2017 de un carcinoma epidermoide de amígdalas palatinas T3N2M0 al cual le realizaron una amigdalectomía un mes después del diagnóstico. Posterior a ello recibió 30 sesiones de radioterapia y 2 sesiones de quimioterapia en total. Fue remitido al servicio de Terapia física de la Clínica Santa Paula 4 meses después de la cirugía debido a las alteraciones posturales que ésta produjo. Asistió a rehabilitación una vez a la semana, durante un año. El abordaje consistió en la aplicación de crioterapia, drenaje linfático manual, masaje liberador de cicatriz, liberación de puntos gatillo, electroterapia, estabilidad espinal y técnicas de terapia manual logrando mejorar ampliamente la evaluación inicial. La rehabilitación oportuna pero a la misma vez continuada (al menos 1 año) en pacientes post cirugía de cáncer de amígdala podría ser beneficiosa para el manejo de las alteraciones posturales que ésta provoca, siendo más efectiva la combinación de técnicas fisioterapéuticas que el uso aislado de las mismas.

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“…[ 6 ] Although its incidence is relatively lower compared with other cancers, it severely affects the quality of life (QoL) in such patients. [ 7 – 9 ] Additionally, its mortality rate also increases year by year. [ 6 , 10 ]…”

Section: Introductionmentioning

confidence: 99%

Quality of life in Chinese patients with laryngeal cancer after radiotherapy

Zhang²,

Luan

et al. 2018

Medicine

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This retrospective study explored the quality of life (QoL) in Chinese patients with laryngeal cancer (LC) after radiotherapy.Fifty-nine eligible patients with Tis-T4 LC were included in this retrospective study. All patients received radiotherapy. Outcomes were measured by the core measure Questionnaire-C30 (QLQ-C30), and the disease-specific Head & Neck cancer module (QLQ-H&N35). All outcomes were assessed before and 3 months after the radiotherapy.Three months after the radiotherapy, all items of QLQ-C30 and QLQ-H&N35 scales changed significantly (P < .05), except the social functioning (P = .09), role activities (P = .81), and global (P = .12) in QLQ-C30 scale and social contacts (P = 1.00), teeth problems (P = .21), trismus (P = 1.00), and feeling ill (P = .07) in QLQ-H&N35 scale, compared with these items before the radiotherapy.The results of this study showed that most items of QoL changed significantly after 3 months of radiotherapy in Chinese patients with LC.

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Tratamiento del cáncer de laringe avanzado y calidad de vida. Revisión sistemática

Cited by 23 publications

References 20 publications

Prognostic Significance of Lymph Node Metastases and Ratio in Laryngeal Squamous Cell Carcinoma

Prognostic Significance of Lymph Node Metastases and Ratio in Laryngeal Squamous Cell Carcinoma

Abordaje fisioterapéutico en las alteraciones funcionales producidas por la cirugía del cáncer de amígdalas palatinas: reporte de caso

Quality of life in Chinese patients with laryngeal cancer after radiotherapy

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