Tratamiento de la psoriasis del cuero cabelludo. Revisión de la evidencia y Consenso Delphi del Grupo de Psoriasis de la Academia Española de Dermatología y Venereología

Puig, L.; Ribera, M.; Hernanz, J.M.; Belinchón, I.; Santos‐Juanes, Jorge; Linares, M.; Querol, I.; Colomé, E.; Caballé, G.

doi:10.1016/j.ad.2010.09.001

Cited by 14 publications

(7 citation statements)

References 86 publications

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“…Although this is similar to the samples used in the preliminary stage of the Delphi process in existing studies,21,23,24 this figure is lower than the preferred number for a Delphi session, and much higher samples were used in the latter stages of previously published research 21,24. Therefore we acknowledge that the low total number of participants may contribute to potential bias.…”

Section: Discussionsupporting

confidence: 56%

“…The effectiveness of the Delphi approach for producing recommendations for new therapeutic directions has already been shown for psoriasis21–23 and epidermolysis bullosa 24. This research provides a balanced consensus that encompasses both physician and patient perspectives, providing a sound basis on which to argue for new directions in topical AK treatment.…”

Section: Discussionmentioning

confidence: 86%

“…Although a minimum of 10 experts is more usual, the size of the Delphi panel has not been shown to have an adverse impact on the validity of the results 20. Delphi panel sample sizes have ranged from 5 to 2865 experts,20 and a similar study using an expert Delphi panel to develop treatment recommendations for scalp psoriasis sought input from seven experts 21. The “real-time” application and relevance of the Delphi process has also been demonstrated 23.…”

Section: Discussionmentioning

confidence: 99%

“…Facilitators categorized the topics generating consensus into themes and issues that were then shared with the participants to confirm that they accurately represented the issues discussed. Issues within themes and emerging critical issues were prioritized using Likert scales, as used in previous consensus studies in dermatology 20,21,23,24. Our experts ranked issues using a six-point Likert scale (1 = least important, 6 = most important).…”

Section: Methodsmentioning

confidence: 99%

“…The Delphi approach unites experts to discuss and make progress on complex issues based on consensus opinion20 and has previously been applied successfully to produce therapeutic recommendations in dermatology in the areas of psoriasis21–23 and epidermolysis bullosa 24. This study convened a modified Delphi approach to generate consensus on factors constraining the real-world efficacy of topical AK therapy and make recommendations for the future development of AK care strategies.…”

Section: Introductionmentioning

confidence: 99%

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A consensus approach to improving patient adherence and persistence with topical treatment for actinic keratosis

et al. 2015

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BackgroundTopical therapy is important in the treatment of actinic keratosis, but guidance for improving adherence/persistence during topical therapy is still lacking.ObjectivesTo utilize expert consensus to generate a list of recommendations to improve real-world efficacy when prescribing topical therapy for actinic keratosis.MethodsAn expert panel of eight dermatologists was convened to generate recommendations based on facilitated discussion and consensus generation using a modified Delphi session. The recommendations were ratified with the expert panel.ResultsFacilitated discussion generated 31 issues within five themes, which were prioritized using expert voting. Consensus was achieved on the importance of short and simple treatment regimens for maximizing patient compliance, physician awareness of the progression of actinic keratosis to squamous cell carcinoma, provision of appropriate patient information, and the use of effective communication strategies to educate physicians about actinic keratosis. Based on these key findings, eight recommendations were generated.ConclusionsThe recommendations will assist physicians when prescribing topical actinic keratosis therapy. Further research should focus on the types of patient outcomes that are influenced by the characteristics of topical field therapy.

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Section: Discussionsupporting

confidence: 56%

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A consensus approach to improving patient adherence and persistence with topical treatment for actinic keratosis

et al. 2015

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Topical treatments for scalp psoriasis

Schlager

Rosumeck

Werner

et al. 2016

Cochrane Database of Systematic Reviews

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Topical treatments for scalp psoriasis Background: People with chronic plaque psoriasis often have lesions on the scalp that are difficult to treat. Our objective was to assess the efficacy and safety of topical treatments for scalp psoriasis. Methods: We searched the following databases up to August 2015: the Cochrane Skin Group Specialised Register, CENTRAL, MEDLINE, EMBASE and LILACS. We also searched five trial registers, screened abstracts of six psoriasis-specific conferences and checked the bibliography of included studies for further references to relevant randomised controlled trials (RCTs). Our quality of evidence assessment was based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group approach. We graded the quality of evidence for the following outcomes: 'clearance' or 'response' as assessed by the investigator global assessment (IGA) and 'response' according to the patient global assessment (PGA), improvement in quality of life, and the number of patients with adverse events (AE) requiring withdrawal of treatment. We expressed the results of the individual studies as risk ratios (RR) with 95% confidence intervals (CI) for dichotomous outcomes, and mean differences with 95% CI for continuous outcomes. If studies were sufficiently homogeneous, we metaanalysed the data by using the random-effects model. Results: We included 59 RCTs, with overall 11.561 participants. Most findings were limited to short-term treatments (< six months). Overall evidence was of moderate quality. According to the clinician and patients' self-assessment a corticosteroid/vitamin D combination (e.g. betamethasone dipropionate plus calcipotriol) and corticosteroids of high and very high potency were more effective than vitamin D. The two-compound combination was superior to the corticosteroid alone, but the additional benefit was small. Reporting of quality of life data was insufficient to be included for meta-analyses and not feasible for quality of evidence assessment. The two-compound combination and corticosteroids caused fewer withdrawals due to AEs than vitamin D. There was no difference between the two-compound combination and corticosteroid monotherapy concerning this outcome. None of the studies stated which AE that caused withdrawal from treatment. However, the risk of withdrawing due to AEs was very small for all three therapies. Due to poor data evaluation of most other topical treatments was limited.

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Adherencia y satisfacción del paciente y características organolépticas y de uso de los tratamientos tópicos utilizados para la psoriasis: Consenso Delphi del panel de expertos y miembros del Grupo de Psoriasis de la Academia Española de Dermatología y Venereología

Puig

Carrascosa

Belinchón

et al. 2013

Actas Dermo-Sifiliográficas

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Tratamiento de la psoriasis del cuero cabelludo. Revisión de la evidencia y Consenso Delphi del Grupo de Psoriasis de la Academia Española de Dermatología y Venereología

Cited by 14 publications

References 86 publications

A consensus approach to improving patient adherence and persistence with topical treatment for actinic keratosis

A consensus approach to improving patient adherence and persistence with topical treatment for actinic keratosis

Topical treatments for scalp psoriasis

Adherencia y satisfacción del paciente y características organolépticas y de uso de los tratamientos tópicos utilizados para la psoriasis: Consenso Delphi del panel de expertos y miembros del Grupo de Psoriasis de la Academia Española de Dermatología y Venereología

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