Tratamento clínico da neurorretinite subaguda difusa unilateral com albendazol

Malaguido, Marcus Rudolph; Casella, Antônio Marcelo Barbante; Malaguido, Daniela Rossetto Garcia

doi:10.1590/s0004-27492007000500016

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…Initially the use of oral anthelmintic was considered ineffective 70 but further studies have shown that thiabendazole is effective in the treatment of patients with a moderate degree of vitritis associated with a breakdown in the blood-retinal barrier. 108 Recent studies report case series of successful treatment of DUSN with albendazole 98,109 (Fig. 107 However, Casella and coworkers reported that ivermectin failed to kill a nematode that was subsequently identified and destroyed with laser photocoagulation.…”

Section: Differential Diagnosismentioning

confidence: 99%

Helminthic Disease

Ávila¹,

Isaac²

2013

Retina

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Section: Differential Diagnosismentioning

confidence: 99%

Helminthic Disease

Ávila¹,

Isaac²

2013

Retina

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Intraocular Nematode

Biswas¹,

Bansal²

2017

Emerging Infectious Uveitis

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Imaging in the Diagnosis and Management of Diffuse Unilateral Subacute Neuroretinitis

Filho¹,

Garcia²,

Arévalo³

2012

International Ophthalmology Clinics

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DUSN is an ocular inflammatory syndrome described by Gass 1 in 1977, and initially called the ''unilateral wipe-out syndrome.'' Later, the term ''diffuse unilateral subacute neuroretinitis'' was introduced and the presence of an intraocular nematode as a causative agent was reported. 2,3 Different sized parasites have been reported as possible etiologic agents of DUSN, including Ancilostoma caninum and Baylissascaris procyonis, however, these reports did not present conclusive evidence of a specific agent. [3][4][5] DUSN is usually unilateral, although bilateral disease has been reported, 6,7 tends to occur in children and young adults, and can lead to severe visual loss if left untreated. The mean age of DUSN patients is16.7 years, with >83% of patients being younger than 20 years. 7 The clinical course of DUSN was described by Gass and Scelfo. 2 The disease has 2 different stages: an early stage characterized by decreased visual acuity, papilitis, multifocal yellow-white lesions, vitritis, and vasculitis (Figs. 1, 2); and a late stage characterized by decreased visual acuity, mild vitritis, diffuse or focal retinal epithelial damage, optic nerve atrophy, retinal vessel narrowing, presence of small white spots (probable exudation residue), and the presence of subretinal tracks, suggesting remnants of larvae migration in the subretinal space (Fig. 3). 2,3,8,9 More recently, Garcia Filho and colleagues reported 121 patients with the clinical diagnosis of DUSN. Most patients presented in the late stage of the disease (92.6%) and the most prevalent clinical features were the presence of subretinal tracks (91.7%), focal alterations of the retinal pigmented epithelium (RPE) (89.3%), small white spots

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Tratamento clínico da neurorretinite subaguda difusa unilateral com albendazol

Cited by 3 publications

References 18 publications

Helminthic Disease

Helminthic Disease

Intraocular Nematode

Imaging in the Diagnosis and Management of Diffuse Unilateral Subacute Neuroretinitis

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