Transverse Testicular Ectopia: A Three-Case Report and Review of the Literature

Naouar, Sahbi; Maazoun, K.; Sahnoun, Lassâad; Jouini, R.; Ksia, Amine; Elezzi, Oumama; Krichène, I.; Mekki, Mongi; Belghith, Mohsen; Nouri, Abdellatif

doi:10.1016/j.urology.2007.11.133

Cited by 38 publications

(40 citation statements)

References 20 publications

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“…Alternatively, both testes, the entire uterus, and both Fallopian tubes have herniated into the same inguinal canal, a condition known as transverse testicular ectopia, which was observed in 3 out of 5 of our patients. This condition is associated with persistence of Müllerian derivatives in 30% of cases [7]. The second so-called ‘female’ variant is less frequent, it is characterized by bilateral abdominal cryptorchidism; both testes are embedded in the round ligament.…”

Section: Discussionmentioning

confidence: 99%

Mutations of the AMH Type II Receptor in Two Extended Families with Persistent Müllerian Duct Syndrome: Lack of Phenotype/Genotype Correlation

et al. 2012

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Our goal was to compare phenotype and genotype in two extended Middle-Eastern families affected by persistent Müllerian duct syndrome due to mutations of the type II anti-Müllerian hormone receptor (AMHR-II). The first, consanguineous, family consisted of 6 boys and 2 girls, the second consisted of 4 girls and 2 boys. In family I, 4 boys and 1 girl were homozygous for a stop mutation in the 9th exon of AMHR-II, removing part of the intracellular domain of the protein. In family II, 1 girl and 1 boy were homozygous for a transversion changing conserved histidine 254 into a glutamine. Both homozygous girls were normal. In the homozygous males, the degree of development of Müllerian derivatives was variable. The uterus was well developed in 2 boys of family I and in the patient from family II; however, in 1 subject from family I, Müllerian derivatives were undetectable. Taken together, the diversity of clinical symptoms within the same sibship and the lack of correlation between the development of the Müllerian derivatives and the severity of the molecular defects suggest highly variable penetrance of the abnormal alleles and/or the existence of other genetic or epigenetic modifiers of gene expression.

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Section: Discussionmentioning

confidence: 99%

Mutations of the AMH Type II Receptor in Two Extended Families with Persistent Müllerian Duct Syndrome: Lack of Phenotype/Genotype Correlation

et al. 2012

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“…In such instances, an ultrasound may be considered to evaluate for the presence of Müllarian structures, especially if the hernia is particularly firm or otherwise unusual. If Müllarian struc- tures are present on ultrasound, karyotyping and a human chorionic gonadotropin stimulation test should be performed to confirm the patient is 46XY with testicular tissue (Naouar et al 2008). Commonly, however, an ectopic testicle is diagnosed intraoperatively.…”

Section: Diagnosismentioning

confidence: 99%

“…Laparoscopy should be strongly considered for the diagnosis of remnant Müllerian structures (Malik et al 2008;Naji et al 2012). However, unless their location interferes with orchiopexy, these do not need to be removed as they are not found to be at risk for malignant degeneration and intervention increases risk of injury to the vas deferens or testicular blood supply (Wuerstle et al 2007;Naouar et al 2008). If orchiopexy is not feasible, orchiectomy should be performed (Naouar et al 2008).…”

Section: Treatmentmentioning

confidence: 99%

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Male Genitourinary System

Shepard

Gayheart

Joseph

2016

Bergman's Comprehensive Encyclopedia of Human Anatomic Variation

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“…Crossed testicular ectopia (CTE) in which both gonads migrate towards the same hemiscrotum is a rare anatomic abnormality that has been reported in about 100 cases [1,2]. Synonymous terms of this pathology include transverse testicular ectopia, testicular pseudo-duplication, unilateral double testes and transverse aberrant testicular maldescent [3].…”

Section: Introductionmentioning

confidence: 99%

Testicular Fusion in a Patient with Crossed Testicular Ectopia: A Rare Entity

Yanaral

Yıldırım

2012

Urol Int

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Crossed testicular ectopia (CTE) is a well-described, rare congenital abnormality of testicular descent, in which both testes migrate through one inguinal canal. The objective of this work is to present a case of fused two testicles in a hemiscrotum as a rare entity of CTE. We describe a rare case of CTE in a 19-year-old boy presenting to the Department with left testis placed in the right hemiscrotum with right inguinal hernia. Ultrasound and magnetic resonance imaging revealed fused testes with their own vasa deferentia in the left hemiscrotum. Azoospermia was detected in semen analysis. The patient was referred to microTESE and ICSI procedure for his infertility problem. CTE should be kept in mind in patients with an inguinal hernia and contralateral nonpalpable testis.

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Transverse Testicular Ectopia: A Three-Case Report and Review of the Literature

Cited by 38 publications

References 20 publications

Mutations of the AMH Type II Receptor in Two Extended Families with Persistent Müllerian Duct Syndrome: Lack of Phenotype/Genotype Correlation

Mutations of the AMH Type II Receptor in Two Extended Families with Persistent Müllerian Duct Syndrome: Lack of Phenotype/Genotype Correlation

Male Genitourinary System

Testicular Fusion in a Patient with Crossed Testicular Ectopia: A Rare Entity

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