Transvaginal versus transabdominal ultrasound guidance for embryo transfer in donor oocyte recipients: a randomized clinical trial

Bodri, Daniel; Colodrón, Marta; García, Désirée; Obradors, Albert; Vernaeve, V.; Coll, O.

doi:10.1016/j.fertnstert.2011.03.028

Cited by 56 publications

(64 citation statements)

References 19 publications

(23 reference statements)

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“…In hormonal replacement cycles, transdermal estradiol patches were started from cycle day 2 and dydrogesterone was added from cycle day 11 after which cleavage-stage embryos or blastocysts were transferred 1 or 7 days later, respectively. All embryo transfer procedures were performed under vaginal ultrasound guidance using a specially designed soft catheter (Kitazato, Japan) by placing a single embryo in minimal volume to the mid-uterine cavity [6]. Dydrogesterone (30 mg/day orally) was routinely administered during the early luteal phase both after fresh and frozen-thawed embryo transfer procedures.…”

Section: Methodsmentioning

confidence: 99%

Minimal ovarian stimulation combined with elective single embryo transfer policy: age-specific results of a large, single-centre, Japanese cohort

Kato¹,

Takehara²,

Segawa

et al. 2012

Reprod Biol Endocrinol

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106

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BackgroundThe two main complications associated with the use of assisted reproduction techniques, ovarian hyperstimulation syndrome and multiple pregnancies, could be eliminated by milder ovarian stimulation protocols and the increased use of a single embryo transfer (SET) policy. A retrospective, cohort study was performed in private infertility centre to evaluate the embryological and clinical results of a large exclusively SET program according to patient age (lower or equal 29, 30–34, 35–39, 40–44 and equal or higher 45 years).MaterialsA total of 7,244 infertile patients have undergone 20,244 cycles with a clomiphene-based minimal stimulation or natural cycle IVF protocol during 2008. Following oocyte retrieval, fertilization and embryo culture a total of 10,401 fresh or frozen single embryo transfer procedures were performed involving cleavage-stage embryos or blastocysts.ResultsSuccessful oocyte retrieval rate (78.0 %) showed no age-dependent decrease until 45 years. Fertilization (80.3 %) and cleavage (91.1 %) rates were not significantly different between age groups. Blastocyst formation (70.1 % to 22.8 %) and overall live birth rates (35.9 % to 2 %) showed an age-dependent decrease. Frozen-thawed blastocyst transfer cycles gave the highest chance of live birth per embryo transfer (41.3 % to 6.1 %).ConclusionsHigh fertilization and cleavage rates were obtained regardless of age whereas blastocyst formation and live birth rates showed an age-dependent decrease. An elective single embryo transfer program based on a minimal ovarian stimulation protocol yields acceptable live birth rates per embryo transfer in infertile patients up until their mid-forties. However in very advanced age patients (equal or higher 45 years old) success rates fall below 1 %.

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Section: Methodsmentioning

confidence: 99%

Minimal ovarian stimulation combined with elective single embryo transfer policy: age-specific results of a large, single-centre, Japanese cohort

Kato¹,

Takehara²,

Segawa

et al. 2012

Reprod Biol Endocrinol

Self Cite

106

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“…Bladder distension may also be uncomfortable to patients. In a study comparing TV versus TA ultrasound for embryo transfer, bladder distension was associated with moderate to severe discomfort in 22% of patients [10]. While intraprocedural pain was not reported in our study, moderate IV sedation is well tolerated when additional analgesia is required.…”

Section: Discussionmentioning

confidence: 50%

“…Multiple prior studies have reported the efficacy of transvaginal catheter placement for management of pelvic fluid collections [1, 5, 7, 9]. Other than 5 reported cases, these studies utilize TV sonography for imaging guidance [5, 10]. In the study by VanSonnenberg et al evaluating transvaginal catheter placement in 14 patients, TA ultrasound was used in the first two patients; however the authors noted better visualization with TV sonography which they used for the remaining 12 patients [5].…”

Section: Discussionmentioning

confidence: 99%

Transvaginal Drainage of Pelvic Abscesses and Collections Using Transabdominal Ultrasound Guidance

Ching

Sumkin

2015

Obstetrics and Gynecology International

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Objectives. To evaluate clinical outcomes following transvaginal catheter placement using transabdominal ultrasound guidance for management of pelvic fluid collections. Methods. A retrospective review was performed for all patients who underwent transvaginal catheter drainage of pelvic fluid collections utilizing transabdominal ultrasound guidance between July 2008 and July 2013. 24 consecutive patients were identified and 24 catheters were placed. Results. The mean age of patients was 48.1 years (range = 27–76 y). 88% of collections were postoperative (n = 21), 8% were from pelvic inflammatory disease (n = 2), and 4% were idiopathic (n = 1). Of the 24 patients, 83% of patients (n = 20) had previously undergone a hysterectomy and 1 patient (4%) was pregnant at the time of drainage. The mean volume of initial drainage was 108 mL (range = 5 to 570). Catheters were left in place for an average of 4.3 days (range = 1–17 d). Microbial sampling was performed in all patients with 71% (n = 17) returning a positive culture. All collections were successfully managed percutaneously. There were no technical complications. Conclusions. Transvaginal catheter drainage of pelvic fluid collections using transabdominal ultrasound guidance is a safe and clinically effective procedure. Appropriate percutaneous management can avoid the need for surgery.

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“…Therefore, the outer catheter does not pass beyond the internal os. The passage of the outer catheter beyond the internal os has been reported to cause uterine contractility . The insertion of the outer catheter into the cervical canal and fixing the tip at the internal os is significant because it allows the inner catheter to pass through the cervical canal barrier‐free.…”

Section: Discussionmentioning

confidence: 99%

Establishment of a trans‐vaginal ultrasound‐guided pinpoint transfer method

Okamoto

2018

Reprod Medicine & Biology

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PurposeThrough the use of the trans‐vaginal ultrasound‐guided pinpoint transfer method, the aim was to ensure the safety of the embryo being transferred in cases of difficult cervixes. It also was aimed to be able to stop embryo transfers in difficult cases and to be able to restart the process under anesthesia or cryopreservation.MethodsA new type of transfer catheter was developed. With this method, after reaching the internal os, the embryologist begins the loading of the embryo into the inner catheter. Then, the embryo transfer begins. Under the guidance of the trans‐vaginal ultrasonography, the optimal position for implantation is selected.ResultsOut of 666 cases, 14 were difficult cervixes. This transfer method enabled 221 of the 666 patients to become pregnant successfully, which was a success rate of 33.2%.ConclusionFrom start to finish, this method takes only 2 min. It is simple, fast, and reliable, with a high satisfaction rate amongst patients.

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Transvaginal versus transabdominal ultrasound guidance for embryo transfer in donor oocyte recipients: a randomized clinical trial

Cited by 56 publications

References 19 publications

Minimal ovarian stimulation combined with elective single embryo transfer policy: age-specific results of a large, single-centre, Japanese cohort

Minimal ovarian stimulation combined with elective single embryo transfer policy: age-specific results of a large, single-centre, Japanese cohort

Transvaginal Drainage of Pelvic Abscesses and Collections Using Transabdominal Ultrasound Guidance

Establishment of a trans‐vaginal ultrasound‐guided pinpoint transfer method

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