Transvaginal repair of anterior vaginal wall prolapse with polyvinylidene fluoride (PVDF) mesh: an alternative for previously restricted materials?

Eslami, Mohammad-Javad; Zargham, Mahtab; Gholipour, Farshad; Hajian, Mohammadreza; Bakhtiari, Katayoun; Hajebrahimi, Sakineh; Eghbal, Melina; Farajzadegan, Ziba

doi:10.1007/s00192-021-04977-7

Cited by 7 publications

(7 citation statements)

References 26 publications

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“…DynaMesh ® -PR4 was initially designed for cystocele repair, with four arms inserted using the double trans-obturator technique (TOT). A trocar is inserted through the foramen obturatorium, over the insertion of the arcus tendinous, but without direct penetration of the sacrospinous ligament [ 9 , 11 ]. Therefore, this technique alone cannot provide adequate apical support, and some patients still require concomitant apical fixation, such as sacrospinal fixation or sacrocolpopexy [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…No sequelae occurred thereafter. In previous studies using PVDF mesh, the mesh erosion rate was about 5 to 6% [ 9 , 11 ] compared to 10–19% with PP mesh [ 8 , 18 , 28 ]. The reduction in mesh erosion observed in our study may be attributed to the double-layer closure method, tension-free mesh fixation, and the advantages of using PVDF material.…”

Section: Discussionmentioning

confidence: 99%

“…However, in certain Asian countries, gynecological/urogynecological specialists continue to utilize mesh more frequently than native tissue for pelvic reconstruction surgery in stages III and IV of POP [ 4 ], with complications being less frequently reported. The key considerations include using an appropriate mesh material [ 11 ] and specialized training in surgical techniques [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

“…In 2017, Barski et al conducted the first cohort study investigating the use of PVDF in urogynecological surgeries [ 9 ]. Similarly, Eslami et al demonstrated the safety of PVDF in anterior vaginal wall repair and the trans-obturator technique (TOT) [ 11 ]. DynaMesh ® PR4 is the only PVDF monofilament mesh implant available worldwide for cystocele repair.…”

Section: Introductionmentioning

confidence: 99%

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Modified Vaginal Mesh Procedure with DynaMesh®-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse

Lin,

Liu,

Hsieh

et al. 2023

Diagnostics

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(1) Background: Treating female pelvic organ prolapse (POP) is challenging. Surgical meshes have been used in transvaginal surgeries since the 1990s, but complications such as mesh exposure and infection have been reported. Polyvinylidene fluoride (PVDF) mesh, known for its stability and non-reactive properties, has shown promise in urogynecological surgeries. (2) Methods: A retrospective analysis was conducted on 27 patients who underwent a modified PVDF vaginal mesh repair procedure using DynaMesh®-PR4 and combined trans-obturator and sacrospinous fixation techniques. Additional surgeries were performed as needed. (3) Results: The mean operation time was 56.7 min, and the mean blood loss was 66.7 mL. The average hospitalization period was 4.2 days with Foley catheter removal after 2 days. Patients experienced lower pain scores from the day of the operation to the following day. Postoperative follow-up revealed that 85.2% of patients achieved anatomic success, with 14.8% experiencing recurrent stage II cystocele. No recurrence of apical prolapse was observed. Complications were rare, with one case (3.7%) of asymptomatic mesh protrusion. (4) Conclusions: The modified vaginal mesh procedure using DynaMesh®-PR4 showed favorable outcomes with a short operation time, low recurrence rate, rare complications, and improved functional outcomes. This surgical option could be considered for anterior and apical pelvic organ prolapse in women.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Modified Vaginal Mesh Procedure with DynaMesh®-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse

Lin,

Liu,

Hsieh

et al. 2023

Diagnostics

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“…The mesh is inserted through small incisions in the vagina or abdomen and secured with sutures. Using the meshes for POP repair is associated with several safety concerns [36]. Unfortunately, the observed adverse effects are related to permanent morbidity and are very difficult to manage.…”

Section: Surgical Management Of Anterior Pelvic Prolapsementioning

confidence: 99%

Different treatment tactics of the pelvic organ prolapse according to the type and the degree of the prolapse: A narrative review

2022

FEM

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Background: Women frequently experience pelvic organ prolapse, significantly impacting their quality of life. Pelvic organ prolapse has a variety of treatment opportunities that should be used to each patient's needs, but the general rule is that only those exhibiting symptoms should receive care. Aim: to evaluate the treatment options for prolapse, depending on the type of prolapse and its degree. Methods: In this review, English studies from common databases such as Pubmed/MEDLINE, Web of science, Scopus, and the Cochrane Library with the keywords “pelvic organ prolapse,” “uterine prolapse,” “vaginal hysterectomy,” combined with keywords, involving “laparoscopic hysterectomy,” were involved. The end date for this review is February 2022. Scientific novelty: The main objective of this paper is to evaluate the treatment options for prolapse, depending on the type of prolapse and its degree. Even though many researchers assessed these treatment options, very few researchers reported about the treatment options according to the degree of prolapse. Many researchers compared surgical interventions for the management of pelvic organ prolapse. Though there are similar works, in the present study, the results of the surgical management depending on the severity of the prolapse were evaluated. The practical significance of the result obtained: The results may help physicians to determine the option of management depending on the degree of prolapse. First-degree (mild) usually does not require any treatment. Second-degree (moderate) may be treated with pessary, exercise, and surgery. Third-degree (severe) may be treated with pessary or surgery. Fourth-degree (complete) may be treated with vaginal hysterectomy, sacrocolpopexy, colpocleisis, and uterosacral ligament suspension. Conclusion: Depending on the surgeon's expertise, using various approaches, pelvic organ prolapse treatment is accomplished in various situations. All previous research indicate that surgery aims to maximise patient satisfaction and return the pelvic organs to their original positions.

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Triple-compartment strategy for abdominal sacral colpopexy using PVDF mesh: one-year report of anatomical and subjective outcomes

et al. 2023

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Transvaginal repair of anterior vaginal wall prolapse with polyvinylidene fluoride (PVDF) mesh: an alternative for previously restricted materials?

Cited by 7 publications

References 26 publications

Modified Vaginal Mesh Procedure with DynaMesh®-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse

Modified Vaginal Mesh Procedure with DynaMesh®-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse

Different treatment tactics of the pelvic organ prolapse according to the type and the degree of the prolapse: A narrative review

Triple-compartment strategy for abdominal sacral colpopexy using PVDF mesh: one-year report of anatomical and subjective outcomes

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