Objective. To evaluate the effectiveness of a modified Wiltse approach to the lumbar spine for extraforaminal disk herniation. Material and Methods. A total of 1020 patients with herniated lumbar intervertebral disc were operated on, out of them 30 (2.9 %) patients were diagnosed as having extraforaminal disc herniations most often observed at the L4-L5 (53.3 %) and L5-S1 (40.0 %) levels. Clinical manifestations included back pain in 20 patients (66.6 %) and radicular syndrome -in all patients, which was accompanied by movement disorders in 15 (50.0 %) cases and by sensitivity disorders in 9 (30 %). Evaluation of surgical results was performed in the early postoperative period and at 3 and 6 months after surgery. Clinical outcomes were assessed using modified MacNab criteria. Results. Based on MacNab criteria, an excellent outcome was observed in 45 %, good -in 42 %, and satisfactoryin 13 % of cases at 6 months after surgery. The volume of intraoperative blood loss was on average 52.8 ± 30 mL, the average length of hospital stay was 2.6 days. Conclusion. The modified Wiltse approach is an effective surgery to remove extraforaminal herniation in the lumbar spine, which allows achieving excellent and good results of treatment in 87 % of cases. Please cite this paper as: Klimov VS, Evsyukov AV, Kosimshoev MA. The modified Wiltse approach for treatment of extraforaminal disc herniation in the lumbar spine. Hir.Статья поступила в редакцию 02. 02.2016 Владимир Сергеевич Климов, канд. мед. наук, врач-нейрохирург, заведующий спинальным отделением; Алексей Владимирович Евсюков, канд. мед. наук, врач-нейрохирург; Муроджон Азамович Косимшоев, врач-нейрохирург, Федеральный центр нейрохирургии, Новосибирск. Vladimir Sergeyevich Klimov, MD, PhD, neurosurgeon, head of the spinal department; Aleksey Vladimirovich Evsyukov, MD, PhD, neurosurgeon in the spinal department; Murodzhon Azamovich Kosimshoev, neurosurgeon in the spinal department, Federal Center of Neurosurgery, Novosibirsk, Russia.